Volume 59 · Issue 12 · 2023

This issue focuses on the research progress of cataract. The responsible editorial committee responsible for the planning, composition and review of this issue is Professor Bao Yongzhen.

With the rapid increase in the myopic population, cataract surgery in individuals with high myopia has become increasingly prevalent. For patients, the benefits of cataract surgery in highly myopic individuals are more pronounced compared to conventional cataract surgery. However, For cataract surgeons, performing cataract surgery in highly myopic individuals presents a more complex surgical procedure with elevated surgical risks and less favorable postoperative outcomes. As a result, the decision regarding the timing of cataract surgery in highly myopic individuals exhibits a clear polarization. some patients with mild cataracts strongly advocate for early surgery, while others with severe cataracts hesitate due to concerns about surgical risks. When making surgical decisions, both medical professionals and patients should thoroughly consider the benefits and risks of the surgery, allowing for an objective selection of the most appropriate timing for the procedure.

Clear lens exchange (CLE) boasts a venerable lineage, its prominence in the field of ophthalmology having incrementally solidified over recent decades, concomitant with the evolution of surgical techniques and the innovation of intraocular lens materials. CLE has assumed a pivotal role in the therapeutic armamentarium for conditions such as glaucoma, high myopia, and presbyopia. Nevertheless, it remains that the sacrifice of accommodation, potentialities of intraoperative and postoperative complications, and less than optimal results in terms of spectacle independence resulting from CLE are not infrequent occurrences. The indiscriminate pursuit of this surgical intervention is inadvisable. It is only by means of a sagacious appreciation of the merits and demerits of CLE, the judicious circumscription of its indicatory ambit, and the bespoke selection of surgical modalities catering to the individual patient, that the superlative outcomes in the realms of surgical efficacy, safety, and patient contentment may be attained.

Cataract is the leading cause of blindness worldwide. In recent years, the annual amount of adult cataract surgery is increasing rapidly. In order to promote the standardization of adult cataract surgery in our country, in accordance with the guiding principles and standards of clinical practice and the existing evidence-based data and expert consensus, Chinese Cataract and Refractive Surgery Society has developed the first clinical guideline in China specifically addressing the surgical treatment of adult cataracts. This guideline focuses on the major clinical issues encountered in adult cataract surgery and aims to provide guidance and reference for ophthalmologists in their clinical practice.

As one of the common infectious corneal diseases, herpes simplex keratitis (HSK) has diverse clinical manifestations, is prone to recurrence, and can lead to blindness. In recent years, as new virus detection technologies, treatment drugs and surgical methods have emerged, there are more options for the diagnosis and treatment of HSK, but many problems still exist. In order to further standardize the clinical diagnosis and treatment of HSK and provide guidance and reference for clinical work, the Ocular Infection Group of Chinese Ophthalmologist Association has gathered relevant domestic experts, and reached this consensus on the diagnosis, treatment, and prevention of HSK through full discussion, on the basis of previous opinions, and in consideration of the latest research progress, relevant guidelines abroad and expert recommendations regarding the clinical care of patients with HSK.

To analyze the relationships between preoperative ocular parameters and postoperative anomalous vaults, and research their predictive diagnostic value.

In this retrospective case series study, 664 eyes from 332 patients underwent posterior chamber phakic intraocular lens (pIOL) implantation at Shanghai Bright Eye Hospital and Wuxi Huaxia Eye Hospital from November 2020 to November 2021. Preoperative ocular parameters, including spherical equivalent, intraocular pressure, horizontal/vertical ciliary sulcus diameters (HCS/VCS), white-to-white diameters (WTW), corneal steep/flat curvature, central corneal thickness, anterior chamber depth (ACD), lens thickness (LT), and axial length were collected. The pIOL vaults were measured 3 months after surgery. Patients were categorized into low vault group, optimal vault group, and high vault group based on whether the vault fell within the ideal range (250 to 750 μm). Using the optimal vault group as a benchmark, receiver operating characteristic (ROC) curves were drawn for each ocular parameter of the low and high vault groups to analyze diagnostic efficiency and cut-off values for abnormal vaults after pIOL operation. Each ocular parameter was used as an independent variable to establish a multivariate logistic regression model for two different vault anomalies. ROC curves were drawn and analyzed again based on the regression results.

Statistically significant differences were observed in WTW, HCS-WTW, ACD, and LT among the three groups. Comparisons between each pair of groups indicated that WTW in the high vault group significantly differed from the other two groups (P<0.05), HCS-WTW in the low vault group significantly differed from the other groups (P<0.05), and ACD and LT explained statistical differences among the three groups (P<0.05), while other parameters showed no differences. ROC curves illustrated that independent ocular parameters such as LT, HCS-WTW, and ACD had clinical predictive diagnostic significance for low vault abnormalities. The area under the curve (AUC), sensitivity, and specificity for these parameters were 0.829(0.952, 0.561), 0.745(0.857, 0.644), and 0.730(0.619, 0.853), respectively. The diagnostic cut-off values were 3.745, 0.020, and 2.975 mm, respectively. The clinical predictive significance of independent ocular parameters in diagnosing the high vault group was poor (AUC<0.7). The predictive Logistic model equation for low vault was Logistic(V₁)=-10.067+5.328·HCS-3.620·WTW+6.263·LT, and the predictive model for high vault was Logistic(V₂)=6.232+1.323·WTW-3.358·LT. The new parameters in the predictive equation significantly improved the diagnostic efficiency of low and high vault abnormalities, reaching 0.884(0.810, 0.824) and 0.736(0.810, 0.554), respectively.

Preoperative predictive diagnostic parameters for postoperative low vault group included LT, HCS-WTW, and ACD, while the high vault group had no independent predictive diagnostic parameters. Logistic regression improved the predictive diagnostic efficiency of abnormal vaults.

To evaluate the accuracy of five intraocular lens (IOL) power calculation formulas for calculating IOL power in patients with previous myopia-corrected corneal refractive surgery.

In this case series study, a total of 30 eyes of 30 patients who had excimer laser corneal refractive surgery for myopia and subsequent cataract surgery in Qingdao Eye Hospital from April 2020 to October 2022 were included. The Pentacam anterior segment analysis system and IOLMaster were used to measure ocular parameters, including axial length, anterior chamber depth, keratometry, lens thickness, and mean true net power (mTNP). Five formulas were used for IOL power calculation: Shammas formula, Olsen formula, SRK/T (mTNP) formula, Haigis-L formula, and Barrett True-K formula. After cataract extraction, we obtained the actual postoperative refraction by measuring the objective refraction. The prediction error was determined as the difference between the actual postoperative refraction and the predicted refraction, and the absolute value of the prediction error was the absolute error. The differences in the calculation errors of the 5 formulas were compared.

Regarding the prediction errors, the results of the SRK/T (mTNP) and Olsen formulas were better than those of Shammas and Haigis-L, and the differences were statistically significant (all P<0.05). The proportion of eyes with an absolute error of 0.50 D for Barrett True-K was highest (70%, 21/30), followed by the SRK/T (mTNP) formula (67%, 20/30). The proportions of eyes with an absolute error within 1.00 D for Barrett True-K, SRK/T (mTNP), and Olsen were all over 80%, with 24 eyes, 24 eyes, and 25 eyes, respectively.

The Barrett True-K formula showed high accuracy in predicting the refraction after cataract extraction in patients with a history of corneal refractive surgery for myopia. The calculation result of the Haigis-L formula was highly unstable.

To investigate the effects of the application of a low addition refractive multifocal intraocular lens (IOL) using the micromonovision design in the non-dominant eye with different degrees of preset myopia on the visual acuity, visual function and visual quality after bilateral cataract surgery.

In this randomized controlled trial, patients who were proposed to undergo bilateral phacoemulsification combined with rotational asymmetric refractive IOL (MF15 IOL) implantation at the First Affiliated Hospital of Zhengzhou University between September 2020 and August 2022 were included. All patients were divided into three groups using the random number method. The target refraction of the IOL in the dominant eye was 0.00 D. Non-dominant eyes were given different preoperative IOL reserve refractions, with the reserved near additional degree>0.20 D and≤0.40 D as the low addition,>0.40 D and≤0.60 D as the medium addition, and>0.60 D and≤0.80 D as the high addition. We compared uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA) and uncorrected near visual acuity (UNVA) of monocular and binocular eyes at 1 day, 1 month and 3 months postoperatively in the 3 groups of patients. Furthermore, the contrast sensitivity, stereopsis, defocus curves and visual quality questionnaire results of binocular eyes were compared at 3 months postoperatively. The statistical methods mainly used were chi-square test, two-factor repeated measures ANOVA, one-way ANOVA, LSD test, Kruskal-Wallis test, and paired t-test.

A total of 110 patients (220 eyes) were enrolled in the study, including 48 males and 62 females, with an average age of (59.74±9.38) years. There were 40 patients (80 eyes) in the low additional degree group, 37 patients (74 eyes) in the medium additional degree group, and 33 patients (66 eyes) in the high additional degree group. The differences in distance, intermediate and near visual acuity of the dominant eyes among the three groups were not statistically significant at different measurement timepoints postoperatively (P>0.05). The differences in intermediate and near visual acuity of the non-dominant eyes were also not statistically significant (P>0.05) among the three groups. In contrast, at 3 months, the UDVA of the non-dominant eyes in the low additional degree group (0.04±0.06) and medium additional degree group (0.04±0.07) was significantly higher than that in the high additional degree group (0.08±0.09) (F=4.776, P=0.011, bias η²=0.086). There was no statistically significant difference in binocular uncorrected distance, intermediate and near visual acuity among the three groups at different postoperative timepoints (P>0.05). The binocular UDVA, UIVA and UNVA (logMAR visual acuity) at 3 months postoperatively were -0.04±0.04, 0.03±0.08, 0.10±0.13 in the low addition group, -0.01±0.05, -0.02±0.06, 0.09±0.10 in the medium addition group, and 0.02±0.07, 0.01±0.09, 0.16±0.11 in the high addition group. At 3 months postoperatively, the binocular contrast sensitivity of the low additional degree group was significantly higher than that of the high additional degree group (P<0.05), except that there was no significant difference at the spatial frequency of 6 cycles per degree in the absence of glare (P>0.05). The binocular contrast sensitivity of the medium additional degree group was significantly higher than that of the high additional degree group at the spatial frequencies of 6 and 18 cycles per degree in the glare condition (P<0.05). The difference in the binocular contrast sensitivity between the low and medium additional degree groups did not reach statistical significance (P>0.05). The peak of the binocular defocus curve in the three groups was significantly wider than that in the monocular eyes, and the decline trend was more gentle, with no trough in the middle, and the visual acuity could be maintained above 0.2 (logMAR visual acuity) in the 0.00 D to -3.00 D defocus range. There was no significant difference in the postoperative near stereopsis results among the three groups (P>0.05), with the percentage of near stereopsis sharpness≤60″ reaching 90.00% (36/40), 89.19% (33/37) and 78.79% (26/33), respectively. The proportions of VF-14 scores≥90 in the postoperative questionnaire were 90% (36/40), 91.89% (34/37) and 81.82% (27/33) for the low, medium and high additional degree groups, respectively. The differences in the probability of photic phenomena and spectacles-independent rate were not statistically significant (P>0.05).

The use of micromonovision design for bilateral implantation of a rotational asymmetric refractive MF15 IOL, with the non-dominant eye reserved for different near additional degrees, can enable cataract patients to have significantly improved binocular full-range vision, visual function and visual quality. When the degree of reserved near additions in the non-dominant eye preoperatively is>0.20 D and≤0.60 D, it can ensure sufficient binocular UDVA, UIVA and UNVA after surgery, and meanwhile help to obtain superior contrast sensitivity and stereopsis, as well as a satisfactory spectacles-independent rate and low incidence of photic phenomena.

To explore and analyze the distribution characteristics of chord μ related parameters, as well as the pupil center′s relative position to the coaxial corneal light reflex on the corneal surface, and the influencing factors in young myopia.

This was a cross-sectional study. A total of 761 myopic patients (761 eyes) were collected from March 2021 to December 2021 in the Refractive Surgery Center of Tianjin Eye Hospital, including 388 males and 373 females, with an average age of (24±6) years. The relationship between age, sex, diopter, anterior and posterior corneal surface parameters, and chord μ related parameters was analyzed, including the x and y absolute values of the pupil center, chord μ length, and angle. The normality of the data was tested using the Kolmogorov-Smirnov test, and the influencing factors of chord μ were analyzed through Pearson and Spearman correlation analysis.

The equivalent spherical degree and chord μ length were (-5.47±1.66) D and (0.178±0.095) mm, respectively. The chord μ length followed an approximately normal distribution. The chord μ length of 266 eyes (35%) was distributed in the range of 0.120 to 0.200 mm, while the chord μ length of 479 eyes (63%) was<0.200 mm, and the chord μ length of 620 eyes (81%) was<0.260 mm. The chord μ angle distribution accounted for the largest proportion in the superior nasal quadrant (45.6%), followed by the superior temporal quadrant (34.3%), the inferior temporal quadrant (10.1%), and the inferior nasal quadrant (10.0%). High myopia (r=0.11, P=0.002) and high astigmatism (r=0.08, P=0.023) were associated with an increase in chord μ length. The higher the degree of myopia, the smaller the chord μ angle (r=-0.09, P=0.019). The larger the ISV (r=0.09, P=0.017), IVA (r=0.08, P=0.025), and IHD (r=0.08, P=0.039) on the anterior surface of the cornea, the longer the chord μ length. The higher the astigmatism of the posterior corneal surface, the greater the absolute value of the Y coordinate of the pupil center (r=0.07, P=0.044), and the longer the chord μ length (r=0.08, P=0.035), and the smaller the chord μ angle (r=-0.08, P=0.032).

The chord μ length of young myopic individuals in China followed an approximately normal distribution, with the majority located in the superior nasal and superior temporal quadrants. High myopia, high astigmatism, and irregular corneal shape are the main factors related to an increase in chord μ length.

To investigate the disparity between the set value of the capsulorhexis ring diameter in ophthalmic surgical navigation systems and the actual capsulorhexis ring diameter projected onto the lens surface.

It was a cross-sectional study. Based on the Gullstrand eye model, the theoretical diameter of the capsulorhexis ring projected onto the lens plane through the cornea was calculated using the law of refraction in the Callisto Eye System. When the anterior chamber depth (ACD) ranged from 2.0 to 4.0 mm and the corneal curvature ranged from 40.00 to 48.00 D, the capsulorhexis ring diameters were calculated after projecting capsulorhexis rings with set diameters of 5.5 mm and 6.0 mm onto the lens plane. Additionally, 40 patients (40 eyes) aged 40 to 85 years who underwent cataract phacoemulsification combined with intraocular lens implantation at the Sixth People′s Hospital of Shanghai Jiao Tong University School of Medicine were selected to validate the theoretical calculations. Among them, 15 were male, and 25 were female, and they were divided into three groups based on the ACD: group A (13 eyes) with ACD<3.0 mm; group B (16 eyes) with 3.0 mm≤ACD<3.5 mm; group C (11 eyes) with ACD≥3.5 mm. One week after surgery, anterior segment images of the eyes were taken, and the actual capsulorhexis ring diameter was measured using the Photoshop image processing software and compared with the set and calculated values.

When the capsulorhexis ring diameters were set at 5.5 mm and 6.0 mm and the corneal curvature was calculated based on the Gullstrand Eye model at 43.05 D, a linear negative correlation was found between ACD and the capsulorhexis ring diameter projected onto the lens plane (P<0.001). When the ACD was set at 2.5, 3.0, and 3.5 mm, and the capsulorhexis ring diameters were set at 5.5 and 6.0 mm, a linear negative correlation was observed between corneal curvature and the capsulorhexis ring diameter projected onto the lens plane (P<0.001). When the capsulorhexis ring diameter was set at 5.5 mm and the patient ACD and corneal curvature data were used for calculations, the capsulorhexis ring diameters projected onto the lens plane for groups A, B, and C were (5.09±0.05) mm, (4.97±0.05) mm, and (4.91±0.07) mm, respectively. When the capsulorhexis ring diameter was set at 6.0 mm, they were (5.56±0.05) mm, (5.44±0.05) mm, and (5.37±0.08) mm, respectively. One week after surgery, the actual measurements of capsulorhexis ring diameters for groups A, B, and C were (5.44±0.20) mm, (5.27±0.28) mm, and (5.25±0.41) mm, respectively, and the differences compared to the calculated values were not statistically significant (all P>0.05), but the differences compared to the set values were statistically significant (all P<0.001).

The capsulorhexis ring diameter projected onto the lens surface by the Callisto Eye system was reduced by 7.33% to 10.48% compared to the set value, and the degree of reduction increased with the increase of ACD and corneal curvature.

The patient is a 33-year-old female who, 11 years ago, underwent bilateral posterior chamber phakic intraocular lens (pIOL) implantation due to myopia. She presented with a 2-year history of declining vision in her right eye and sought medical attention. She received femtosecond laser-assisted cataract surgery combined with pIOL extraction. Anterior segment optical coherence tomography and ultrasound biomicroscopy both showed an inverted pIOL in the right eye. Good visual results were achieved, and there were no complications during the six-month follow-up.

A 56-year-old male patient sought medical attention due to a gradual decline in bilateral visual acuity, which had been ongoing for a year and had rapidly worsened over the past three months. He received an initial diagnosis of bilateral concurrent cataracts and bilateral anterior megalophthalmos. Subsequently, cataract removal surgery was performed. During the surgery, it was observed that the patient had lax and fragile zonules of the crystalline lens. To address this issue, the surgical team employed reverse optic capture technique for the implantation of a three-piece intraocular lens. Following the surgery, the patient experienced a substantial improvement in uncorrected visual acuity. Remarkably, the patient remained free from adverse reactions, such as elevated intraocular pressure, during a follow-up period extending to 11 years.

Surgeon introduction Tian Bei, MD, chief physician, associate professor. Member of the Standing Committee of China Sports Rehabilitation Education College of Chinese Medical Association, Member of Sports Medicine Branch of Chinese Medical Association, Member of the Optometry Group of Ophthalmologist Branch of Chinese Medical Doctors Association, Member of the Standing Committee of Diabetes Professional Committee of China Geriatric Health Care Association, Member of Ophthalmology Professional Committee of China Medical Equipment Association, Member of Diabetic Ophthalmology Group of Diabetes Professional Committee of China Research Hospital Association. Vice Chairman of the 13th Health and Wellness Committee of China Democratic League, corresponding editorial board of Chinese Journal of Ophthalmology. Honorary Institute, Senior Visiting Scholar, Royal Murphy Eye Hospital, UK, and Member of Vitreoretinal Surgery Association, UK and Ireland. He has been engaged in the first-line clinical work of ophthalmology in Beijing Tongren Eye Center, Beijing Tongren Hospital affiliated to Capital Medical University for more than 20 years. He is good at vitreoretinal surgery, phacoemulsification cataract aspiration, fundus laser surgery, etc. So far, he has more than 10,000 surgical experiences.

The patient was a 32-year-old female. He went to Jinan Mingshui Eye Hospital because the vision under his right eye was occluded for 1 week. The patient had poor visual acuity in both eyes since childhood and was diagnosed with Marfon's syndrome in an external hospital 10 years ago, which was not treated. History of ocular trauma and surgery was denied, and other systemic medical history was denied. The patient's mother suffered from Marfon's syndrome and died of heart disease (details unknown). Full body examination: height 1.75 m, tall and lean body type, spider-like fingers (toes); Cardiac ultrasound Doppler examination revealed mitral valve prolapse with mild-moderate regurgitation, aortic widening with moderate regurgitation, and mild tricuspid valve regurgitation. Eye examination: both eyes were 0.1 for naked eyes and 0.3 for corrected eyes (right eye: -13.50 DS-5.50 DC x 135°; Left eye: -5.50 DS-3.50 DC x 10°); IOP was 14 mmHg (1 mmHg =0.133 kPa) in the right eye and 11 mmHg in the left eye; The conjunctiva of the right eye is not congested, the cornea is transparent, the anterior chamber is moderately deep, the aqueous humor is clear, the lens is displaced to the nasal side (12: 00 to 5: 30), the temporal lens is incomplete, the suspensory ligament of the lens is visible (A in the essence picture 1), the vitreous body is flocculous and opaque, the optic disc boundary is visible in the fundus, the color is normal, there are no obvious abnormalities in the arteries and venous large blood vessels, the retina is bulged from 10: 00 to 2: 00, the retinal hole is visible at about 12: 00, and the fovea is unclear; The conjunctiva of the left eye is not congested, the cornea is transparent, the anterior chamber is moderately deep, the aqueous humor is clear, the lens is displaced to the nasal side (6: 00 to 3: 00 orientation), the temporal lens is incomplete, the suspensory ligament of the lens is visible (B in the essence picture 1), the vitreous body is slightly opaque, the optic disc is visible in the fundus with clear boundaries and normal colors, there are no obvious abnormalities in the arteries and venous large blood vessels, and the fovea is unclear. Clinical diagnosis: Marfon's syndrome; Binocular lens subluxation with incomplete formation; Rhegmatogenous retinal detachment in right eye; Refractive error (anisometropia) in both eyes.

The patient was a 70-year-old male. Because of blurred vision in his left eye for more than 1 year, he went to the Department of Ophthalmology, Affiliated Hospital of Jining Medical College. Has a history of chronic bronchitis. Eye examination: left eye naked visual acuity of 0.04 (uncorrectable), accurate light localization, intraocular pressure of 21 mmHg (1 mmHg =0.133 kPa); The conjunctiva is not congested, the cornea is transparent, the central depth of the anterior chamber is acceptable, the peripheral depth is greater than 1 corneal thickness, the iris is clear in texture, the pupil is round, about 3 mm in diameter, the light response is normal, and the annular gray-white debris-like substance deposits can be seen on the pupil margin; Nuclear opacity of the lens, the nucleus is dark yellow, gray-white debris-like substance deposits can be seen on the anterior surface of the lens, an intermediate disk approximately consistent with the diameter of the pupil can be seen after dilatation of the pupil, and frost-white granular substance deposits can be seen on the anterior surface of the temporal and nasal peripheral lens (Quintessential Picture 1); The optic disc of the left eye is clearly bounded and pale in color. The diameter ratio of the optic cup to the optic disc is about 1.0. The retina is flat, and the macular area is scattered with drusen. Clinical diagnosis: Left eye pseudolens capsule exfoliation syndrome; Secondary glaucoma in left eye; Cataract in the left eye.

The patient was a 50-year-old female. Because the visual acuity of his left eye decreased for more than half a month, he went to Yichang Huaxia Eye Hospital. In 2008, he was injured by a stone in his left eye without surgery; In 2009, the left eye underwent lens dislocation and lens excision without intraocular lens implantation; In 2010, intraocular lens suspension with iris septum was performed in the left eye. Eye examination: visual acuity was 0.4 in the right eye and 30 cm manual in the left eye, which could not be corrected; The cornea of the left eye is transparent, the anterior chamber is medium-deep, the iris is atrophied, the pupil is dilated, the diameter is about 9.0 mm, the intraocular lens is disengaged into the vitreous cavity below the nose, the suspension line above the temporal is disengaged, and the vitreous body is mildly opaque; The optic disc is vaguely visible in the fundus, with clear boundaries and reddish color, flat retina, depigmentation of the peripheral retina, and occlusion of the inferior branch veins (essence pictures 1 and 2); The right eye examination showed no obvious abnormalities. Clinical diagnosis: dislocation of intraocular lens in left eye.

Posterior chamber phakic intraocular lens (pIOL) implantation has been widely adopted for the correction of refractive errors. Among pIOLs, the Implantable Collamer Lens is the most common choice. The selection of the appropriate pIOL size and achieving the desired postoperative vault to minimize complications has consistently been a focal point in academic research. With the advancement of ophthalmic biometric measurement technology and the application of artificial intelligence in the field of medicine, numerous new technologies and methods for pIOL size selection and vault prediction have emerged in recent years. This paper provides a comprehensive review on the topic of how to choose the pIOL size and predict the vault.

Biallelic pathogenic variants in the USH2A gene result in Usher syndrome type Ⅱ and non-syndromic retinitis pigmentosa, both of which entail the progressive loss of photoreceptors leading to blindness. The cDNA of the USH2A gene is extensive, consisting of 15 606 base pairs, rendering it impractical for delivery via adeno-associated virus vectors for gene replacement therapy. Notably, exon 13 has emerged as a focal point for therapeutic intervention, given its predilection for harboring the most pathogenic variants within USH2A. Recent intervention studies targeting USH2A exon 13 through the utilization of antisense oligonucleotides, genome editing, and RNA editing approaches have exhibited promising therapeutic potential. This paper provides a comprehensive overview of the molecular mechanisms, outcome data, and the challenges associated with the application of these interventions in this domain.

On the basis of 3D printing technology, 3D bioprinting has emerged with great development potential and good prospects in the field of medicine and tissue engineering. With this technique, different types of cells and biomaterials can be precisely incorporated into 3D anatomical structures, achieving tissue substitutes with superior structures or functions. In recent years, great progress has been made in the application of 3D bioprinting in ophthalmology. This article reviews not only the differences between 3D printing and 3D bioprinting, but also the development, types, characteristics, application, and prospects of 3D bioprinting in the production of eye tissue engineering materials.

In the article "Relationship between the cross-sectional area of intraretinal capsule cavity of idiopathic macular hole and retinal blood flow density and its effect on retinal function" published in Volume 59, Issue 11, 2023, this journal should read "Gui Chenwei is a graduate student of the First Clinical Medical College of Shanxi Medical University". Corrections are hereby made.