2022年 · 第102卷第45期

Statins can improve the survival rate of patients with atherosclerotic stroke and have pleiotropic benefits such as anticancer, anti-inflammatory, antioxidant, anti-proliferative and plaque stabilization in addition to lipid lowering. Among them, anti-cancer effects are mainly through anti-proliferation, pro-apoptosis, migration and inhibition of invasion. However, it is unclear whether statins provide additional survival benefits for stroke patients with a history of cancer.

The mortality and disability rate of acute basilar artery occlusion are high with simple drug therapy, but the efficacy and safety of thrombectomy for this part of patients always lack high-level evidence-based evidence to support. The purpose of this study was to evaluate the efficacy and safety of endovascular mechanical thrombectomy in patients with acute basilar artery occlusion within 6 to 24 hours of onset.