prolonged postoperative ileus (PPOI) is a common complication after abdominal surgery, which can increase the incidence of postoperative complications, prolong the length of hospital stay, and increase the hospitalization cost[1,2]。 The definition of PPOI is controversial. The incidence of PPOI reported in the literature varies greatly, and it has not gained widespread attention from clinicians in China. There is also a lack of unified diagnostic criteria, and the clinical evidence of related factors is insufficient. We carried out a multi-center case registry study on the occurrence and influencing factors of delayed postoperative intestinal paralysis in abdominal surgery, in order to clarify the incidence of PPOI in patients undergoing open surgery in China, analyze its related factors, and provide reference for clinicians to take effective intervention measures. The results are reported below.