Parkinson's disease (Parkinson's disease) is a common degenerative disease of the central nervous system. The main clinical manifestations are tremor, hypomobility, rigidity, postural balance disorder and other motor symptoms. In addition to motor dysfunction, non-motor symptoms such as depression, anxiety and psychotic disorders of different degrees are also common, which affect the quality of life, daily function and prognosis of patients. In recent years, it has gradually attracted much attention. It has been reported that the incidence of depressive disorder in patients with Parkinson's disease is 40% ~50%, and the incidence of anxiety disorder is 3.6% ~40.0%. Depression and anxiety disorder often coexist and can appear before the motor symptoms of Parkinson's disease. The incidence of psychotic symptoms in patients with Parkinson's disease without dopaminergic drugs is 5% to 10%, and that in patients with Parkinson's disease treated with dopaminergic drugs is 10% to 40%[1,2]。 It can be seen that depression, anxiety and psychotic symptoms are more common in Parkinson's disease, which affect the quality of life and social function of patients, and increase the heavy burden of caregivers[3,4,5]。 However, at present, domestic clinicians pay insufficient attention to this, and there are few related studies. In order to better guide clinical practice and promote relevant research progress in China, it is necessary to formulate diagnostic criteria and treatment guidelines for depression, anxiety and psychotic disorders in Parkinson's disease in China.
