2012年 · 第50卷第03期

Professor Tang Zeyuan, former deputy editor-in-chief of Chinese Journal of Pediatrics, died on November 7, 2011 due to illness. Professor Tang Zeyuan has served as a member of the 7th and 8th editorial committee, deputy editor-in-chief of the 9th editorial committee and consultant of the 10th editorial committee of Chinese Journal of Pediatrics.

The pathophysiological process of sepsis involves a highly complex and integrated response of the body, including the activation of various cells, inflammatory mediators, and the coagulation system. In 1994, Lam C used in vivo microscope to observe the microcirculation of septic rats with stable blood pressure in vivo, and proposed for the first time that there were microcirculation changes in the early stage of sepsis; In 1999, orthogonal polarization spectroscopy (OPS) entered clinical application, which confirmed that the changes of sublingual microcirculation and internal organ microcirculation were basically consistent, which made scholars at home and abroad reach a consensus on the existence of microcirculation changes in the early stage of sepsis. In recent years, more and more studies suggest that microcirculation dysfunction is an important pathophysiological basis in the development of systemic inflammatory response syndrome (SIRS), sepsis and multiple organ dysfunction syndrome (MODS)^[1,2]Early treatment to improve microcirculation is the fundamental measure to protect the function of important organs. This article reviews the mechanisms, evaluation methods and clinical significance of microcirculatory disorders in sepsis.

More and more studies have shown that the indicators of onset of puberty, such as menarche and breast development Tanner stage II (B2), are early in developed countries^[1,2]。 Changes in the initiation phase of adolescence, such as the advancement of the average age of menarche, have attracted attention in most developed and developing countries in the 20th century^[3,4]。 The phenomenon of early youth initiation in our country has lasted for at least 20 years. The data of the "Physical Health Study of Chinese Students" which took place every 5 years since 1985^[5]As well as the recent findings of the Collaborative Group on Adolescent Development Investigation^[6]All of them clearly show that the long-term trend of youth initiation is gradually emerging, especially in rural areas.

follicular lymphoma (FL) is one of the most common malignant lymphomas in adulthood, second only to diffuse large B cell lymphoma (DLBCL)^[1]。 The majority of B-cell-derived malignant lymphomas in children and adolescents are Burkitt's lymphoma, diffuse large B-cell lymphoma, lymphoblastic lymphoma and other aggressive lymphomas; FL in children reported abroad does not exceed 2% of all types of lymphoma in the same age group^[2]And there are few domestic studies. Recent foreign studies suggest that childhood FL is different from adult FL and other types of childhood lymphoma in terms of clinical characteristics, cytogenetics, molecular biology and prognosis. 2008 WHO 4th edition classification of hematopoietic and lymphoid tissue tumors^[3]When updated, it temporarily distinguished childhood FL from adult FL as an independent disease.

The American Academy of Pediatrics (AAP) -sponsored American Pediatrics and Exhibitions Congress was held October 15-18, 2011 at the Boston Convention and Exhibition Center in the United States with 13,000 delegates from around the world. Nearly 40 representatives from China, including professors Yang Xiqiang, Dai Yaohua and Song Guowei, attended the event.

The 11th Asian Congress of Pediatric Nephrology (ACPN), sponsored by the Asian Pediatric Nephrology Association (AsPNA), was successfully held in Fukuoka, Japan, from June 2 to 4, 2011. The event was attended by 523 delegates from 20 countries and regions, including 23 representatives from mainland China, including Beijing, Shanghai, Dalian, Zhanjiang and Guiyang, as well as representatives from Hong Kong and Taiwan.

Dr. Chen Xuwen(435200 Department of Pediatrics, Yangxin County People's Hospital, Hubei Province) Q:

In December 2010, the Ministry of Health launched the first batch of national key clinical specialty projects, and pediatrics critical care medicine (PCCM) was listed as the only subspecialty in pediatrics. This is undoubtedly a milestone event in the development history of PCCM in China. She clearly showed that PCCM in China has become independent of children's emergency medicine, and as a tertiary discipline under pediatrics, it has been officially recognized and highly valued by the national health administration. At the same time, it also indicates that the construction of PCCM and pediatrics intensive care unit (PICU) as its practice base and objective subject in China is about to enter a brand-new stage. Therefore, we will briefly describe our opinions on strengthening the construction of the theory and technology system of PCCM in China.

The author systematically reviewed and analyzed all the papers published in Chinese Journal of Pediatrics in the past 10 years. The results showed that from 2001 to 2010, 3209 papers were published in Chinese Journal of Pediatrics, of which 2073 papers were cited, accounting for 64.60%. The total citation frequency was 18 546 times, the average citation was 5.78 times, and the highest citation was 990 times for a single article. The article "Standards, Protocols and Guidelines" was cited 62.92 times, and the article "Fast Track" was cited 16.20 times. The key articles were all cited 7.90 times. The articles in the columns of "Commentary", "Monograph", "Opinion, Controversy and Discussion" have been cited as much as 6.50 times. The average citation of the grant-funded papers was 4.81 times, which was lower than the average citation of 5.78 times, and slightly higher than the average citation of 4.36 times of the non-grant papers after removing "standards, programs and guidelines".