Volume 50 · Issue 01 · 2014

After a season of cold winter, the earth conveys the message of early spring, and 2014 is coming towards us. Looking back at 2013, when we shook hands and said goodbye, this journal has made remarkable achievements. The indexes of various journals continue to improve, ranking first among ophthalmology journals; In the comprehensive evaluation ranking of 1994 Chinese scientific and technological journals, the total score has been raised from 90th to 30th. What is most happy is that this journal has once again won the title of 100 Chinese outstanding academic journals. This is the result of the joint efforts of all ophthalmology colleagues, and we are proud of it! In the future years of running a journal, on the one hand, we should continue to develop our advantages, adhere to the tenet of respecting science, seeking truth and pragmatism, pay attention to academic norms, advocate original research, standardize the content and submission process of authors' manuscripts, adhere to the review system of "three reviews and five determinations", and undertake the mission of spreading the research achievements, major breakthroughs and research trends of ophthalmology and vision science in China.

Strategies and methods of myopia prevention and control has been more and more.In recent years optical correction method is focusing on promoting the retinal mid-peripheral myopic defocus,improving the visual quality and promoting the accommodative function.Among the all,orthokeratology is the most notable optometry technology.This article will combine research progress both local and international achievements,the present situation of the domestic popularized the technique,and the existing problems.From the realistic approach,keep improving,the pursuit of stability,the pursuit of harmony and eliminate the false five aspects,to discuss how to promote orthokeratology for the myopia control with longterm stably efficacy and safety.How to promote the harmony and cooperation between doctors,patients and manufactures.And how to correctly guide the orthokeratology Having both specification and continued development.

With the development of information technology and urbanization,the prevalence of myopia in Chinese children is rising each year,meanwhile,there appears to be some cognitive and behavioral misunderstanding about the prevention and treatment of myopia now.To control the development of myopia,we should make efforts to focus on prevention of myopia,promote scientific ways of diagnosis and treatment,as well as implement integrated project.

Objective To evaluate the impact of amplitude of accommodation on controlling the development of myopia in orthokeratology.Methods Forty-nine children aged 7 to 14 years were enrolled in this prospective clinical study.Orthokeratology was performed to correct the refractive errors of these children after measurement of refraction,corneal topography,amplitude of accommodation and axial length.Axial length (AL) and amplitude of accommodation was measured after theatment.The average amplitude of accommodation was calculated and was used as the cutting point for dividing the cohort into " amplitude of accommodation above average" vs." amplitude of accommodation below average".Data were analyzed by paired t-test,independent t-test,repeated measures-ANOVAs and Pearson correlation analysis.Results The AL before and after 1-year and 2-year treatment was (24.98 ± 0.75) mm,(25.13 ± 0.74) mm and (25.32 ± 0.78) mm,respectively.AL increased significantly throughout the observed 24-month period (F =75.848,P ＜0.001).Amplitude of accommodation increased from(13.68 ±2.65)D to(16.12 ±2.41) D in 2 years(t =-6.461,P ＜ 0.001)and amplitude of accommodation significantly affected axial growth (F =7.395,P =0.009).The axial growth of subjects with below average amplitude of accommodation and those with above average amplitude of accommodation was (0.23 ± 0.25) and (0.44 ± 0.30) mm,indicating a statistically difference(t =-2.719,P =0.009).AL change in subjects with below average amplitude of accommodation was 55.81％ that of the subjects with above average amplitude of accommodation.Baseline amplitude of accommodation was positively correlated to axial growth at 24-month visit (r =0.502,P ＜0.001).Linear regression analysis was used between baseline amplitude of accommodation and 2-year axial growth:Axial growth =0.055 · Baseline amplitude of accommodation-0.409 (F =15.806,P ＜ 0.001).The change of amplitude of accommodation for subjects with below average amplitude of accommodation and those with above average amplitude of accommodation after 2-year was (4.04 ± 2.16) D and (0.91 ± 2.15)D,indicating statistically difference(t =5.084,P ＜ 0.001).Conclusions Myopic control effect would be more beneficial to lower amplitude of accommodation children than that to higher amplitude of accommodation children in orthokeratology.The enhancement of accommodation provides some basis for slowing myopia progression with orthokeratology.

In recent years, the concept of cataract refractive surgery has penetrated into the clinical diagnosis and treatment of cataract diseases, and it is the higher pursuit of cataract surgeons to restore better visual quality to patients. More advanced cataract surgery technology and equipment, multifocal intraocular lens, astigmatism correction intraocular lens and aspheric intraocular lens have attracted more and more attention of ophthalmologists for their continuously improved clinical manifestations.

Objective To evaluate and investigate the distribution of corneal density and its Correlation with stray-light value in adult and healthy eyes.Methods A prospective study.Human corneal specimens ranging in age between 20 and 49 years,116 patients (232 eyes) in total,divided into three groups:20-29,30-39,40-49.Pentacam was used to evaluate total corneal average density and corneal thickness at different diameter around the corneal apex,for corneal density were ≤ 2 mm,＞ 2 mm and ≤6 mm,＞6 mm and ≤10 mm,for corneal thickness were 2 mm,6 mm and 10 mm,C-quant was used for the stray-light value.Software SPSS 17.0 was used for statistical analysis.Independent samples t testing mothed was applied to compare the corneal densitometry in different gender and between left eyes and right ones,One-way ANOVA was applied to analyze the differences of corneal density in different age groups and diameters.Pearson correlation analysis was applied to assess the correlation in corneal densitometry values of different diameters,between corneal density of different diameters and age,corneal density of different diameters and corneal thickness of different diameters,corneal density of different diameters and stray-light values.Results Corneal density for ≤2 mm,＞2 mm and ≤6 mm,＞6 mm and ≤10 mm diameter are 10.1±1.5(8.2-16.7),9.3±1.3(7.9-14.2),9.6±1.7(7.3-16.2).Corneal density of ＞6 mm and ≤10 mm diameter in different age groups were 8.9± 1.1,9.3 ± 1.2,10.7±2.1,there was a statistical difference in these values(F =28.939,P =0.000),and there was a positive correlation between corneal density of ＞ 6 mm and ≤ 10 mm diameter and age (r =0.417,P =0.000),There were no statistical differences in corneal density values of ≤ 2 mm and ＞ 2 mm and ≤ 6 mm in different age groups (F =1.575,1.436 ; P ＞ 0.05),and they had no correlation with age (r =0.002,0.048 ; P ＞ 0.05).There was no statistical difference in corneal density in different gender (t =1.744,1.647,-1.181 ; P ＞ 0.05).Corneal density values of left eyes and right ones had positive relationships at the same diameter (r =0.977,P =0.000;r =0.992,P =0.000;r =0.933,P =0.000),and there were no statistical differences (t =0.124,0.199,-0.020;P ＞ 0.05).Between corneal density values of different diameter,there are also some positive relationships,＞6 mm and ≤10 mm and ≤2 mm (r =0.710,P =0.000),＞6 mm and ≤10 mm and ＞2 mmand ≤6mm (r=0.748,P=0.000),≤2 mm and ＞2 mm and ≤6 mm (r=0.973,P=0.000),relationship between ≤2 mm and ＞2 mm and ≤6 mm,＞2 mm and ≤6 mm and ＞6 mm and ≤10 mm was obvious,and there was statistical difference in them (F =17.057,P =0.000).The ocular straylight value was 0.95 ±0.19(0.48-1.38),Corneal density values of ≤2 mm,＞2 mm and ≤6 mm and ＞ 6 mm and ≤ 10 mm diameter had positive relationships with the straylight value (r =0.134,0.146,0.159,P =0.042,0.026,0.016).Conclusions Corneal density can be influenced by age,the influence from age infected the corneal density of peripheral more.There was no correlation between corneal density and corneal thickness.There were some influences of corneal density of healthy eyes to the ocular straylight.

Objective To compare the higher order aberration of wavefront-guided aspherical versus wavefront-guided and Q-value guided aspheric personalized LASIK surgery in the treatment of myopia.Methods Prospective study.120 patients with myopia and/or astigmatism(240 eyes) were involved in our hospital from August 2010 to December 2010.There was a prospective study,divided into three groups:Wavefront-guided aspherical personalized LASIK in group A; Wavefront-guided LASIK in group B; Q-value guided aspheric LASIK in group C.The follow-up time was 6 months.The comparison of data before and after operation was two independent samples t test.The comparison among three groups was one-way analysis of variance,and multiple comparison between groups was Dunnet t test.Results A group:The differences between before and after surgery were not statistically significant in higher order aberration(t1 week =0.874,P1 week =0.387;t1 mouth =-1.145,P1 mouth =0.259;t3 mouth =0.652,P3 mouth =0.518; t6 mouth =0.496,P6 mouth =0.439),but as the extension of time,The values have a tendency to become smaller; the difference was notstatistically significant in spherical aberration between before and after surgery 1 week (t =-1.815,P =0.077),and was statistically significant between before and after surgery 1 month,3 months and 6 months after surgery (t1 month =-4.410,P1 mouth =0.000 ; t3 mouth =-2.375,P3 mouth =0.022 ; t6 mouth =-1.870,P6 month =0.000),the values after surgery were higher.The differences between before and after surgery were not statistically significant in coma aberration (t1 week =1.028,P1 week =0.310; t1 mouth =0.847,P1 mouth =0.402;t3 mouth =0.210,P3 mouth =0.984; t6 mouth =0.533,P6 mouth =0.597).At 6 months,the higher order aberration and spherical aberration in A group and C group were significantly lower than the B group,and the differences were statistically significant(PA&B =0.000; PC&B =0.000),the differences between A group and C group were not statistically significant in higher order aberration and spherical aberration (P =0.866),but A group is less than the C group in changes before and after surgery.The differences among three groups were not statistically significant in the vertical and horizontal coma(Frertical coma =0.367,Pvertical come =0.683;Fhorizontal coma =0.254,Phorizontal coma =0.797).Conclusion Wavefront-guided aspherical personalized LASIK compared with wavefront-guided personalized LASIK can better reduce the increases of the higher order aberration and spherical aberration,and the changes between preoperative and postoperative is less than Qvalue guided aspheric personalized LASIK.

Objective To compare the accuracy of axial length measurement with three methods,that is,immersion B-scan,contact A-scan,and IOLMaster in high myopia with cataract.Methods To analyze the data of the 40 patients (66 eyes),who were all high myopia with cataract and accepted the phacoemulsification and fold-able lens implantation surgery in our hospital from Jan 2012 to May 2012.The measurement of axial length was performed respectively in 66 eyes by immersion B-scan,contact A-scan and IOLMaster.Keratometric power was measured preoperatively by IOLMaster.The IOL power calculation was carried out according to SRK/T formula in the basis of IOLMaster.Their refraction outcome was follow-up three months after operation.Results The axial length was (27.91 ± 1.96) mm,(27.71 ±2.15)mm,(27.88 ± 2.04) mm respectively by immersion B-scan,A-scan and IOLMaster.There was no significant difference between immersion B-scan and IOLMaster method (t =0.726,P =0.473).But the axial length measured by contact A-scan was shorter than that tested by immersion B-scan(t =2.223,P =0.003) and IOL Master(t =2.614,P =0.014)significantly.There was significant difference between immersion B-scan and contact A-Scan method in those patients whose mean absolute refractive error (MARE) was within ± 0.50 Diopter three months after operation(x2 =5.67,P ＜ 0.05),while there was no significant difference between immersion B-scan and IOLMaster measurement (x2 =0.06,P ＞ 0.05).The same situation happened in those patients whose MARE was within ± 1.00 Diopter.That means,there was significant difference between immersion B-scan measurement and contact A-scan measurement (x2 =4.19,P ＜0.05),while there was no significant difference between immersion B-scan and IOLMaster measurement (x2 =0.36,P ＞ 0.05).Conclusions The immersion B-Scan measurement is better than A-scan,and it is as accurate as the IOL Master measurement,which is another good choice for the axial length measuring in high myopia with cataract cases.

In order to advocate the majority of ophthalmologists to pay attention to the improvement of cataract surgery technology and improve the clinical application level of cataract surgery in China, the Chinese Journal of Ophthalmology of Chinese Medical Association and the Cataract and Intraocular Lens Group of Ophthalmology Branch jointly sponsored the "2003 Cataract Surgery Video Competition" in May 2013. In 6 months, a total of 86 cataract surgery videos from all over the country were received. After the review by the jury composed of members of the Cataract and Intraocular Lens Group of the Ophthalmology Branch, a total of 1 first prize, 2 second prizes and 3 third prizes were awarded. This event is co-organized by Abbott Eye Health.

Objective Pathological myopia (PM) is a hereditary ocular disease leading to severe loss of visual acuity and blindness.Lumican gene (LUM) is one of those candidate genes of PM.The purpose of this study was to establish a mutant Lumican transgenic mouse model,and to prepare for the further study of the pathogenesis of PM.Methods Experimental study.Mutation of LUM gene was created by site-directed mutagenesis.Recombinant DNA techniques were used for the construction of the pRP.EX3d-EF1A ＞ LUM/flag ＞ IRES/hrGFP transgene.The gene fragments were microinjected into the zygote male pronuclei of BDF1 mice,and then the zygote cells alive were transplanted into the oviduct of acceptor pregnant female ICR mice.The F0 generation transgenic mice obtained were named C57-TgN (LUM) CCMU.Genome DNA from mice tail was detected by PCR and Western blotting.Results Six of 31 F0 generation mice were positive transgenic mice.The western blotting study showed that the flag-tag was expressed in the mouse tail tissue.Sixty-eight of 128 mice (F1 to F3 generation) were positive transgenic mice,the positive rate is 53.13％.Conclusions The mutant Lumican (cDNA 596T ＞ C) transgenic mouse model has been established.This model will provide fundamental conditions for studies of the pathogenesis of PM.Also it will be the basis of further studies about the effect of Lumican mutation on the development of PM and structure and function of the extra cellular matrix.

With the approval of Ophthalmology Branch of Chinese Medical Association, the 14th National Academic Conference on Corneal and Ocular Surface Diseases and the 6th National Academic Conference on Corneal Refraction will be held in Shanghai from April 24 to 27, 2014. The Keratology Group of Ophthalmology Branch of Chinese Medical Association and the organizer of the conference-Eye, Ear, Nose and Throat Hospital affiliated to Fudan University sincerely invite domestic and foreign ophthalmologists, colleagues and ophthalmology business people to attend.

Objective To investigate the effects and mechanism of amniotic extraction on corneal healing after photorefractive keratectomy (PRK).Methods Experimental Study.Thirty-six New Zealand rabbit corneas were performed with PRK models (-10 diopters,6.5 mm diameter).According to random number table,all eyes were divided into three groups,including treated with amniotic extraction,0.1％dexamethasone and excipient respectively after operation.Clinical and histopathologic examinations were taken by slit-lamp microscope and fight microscope.Corneal epithelium reparation was observed by fluorescent staining.Corneal stroma cell apoptosis was evaluated by terminal deoxyribonucleotidy transferasemediated deoxynuridine triphophate nick end labeling (TUNEL) assay.Myofibroblast generation was evaluated by immunofluorescence checking the expression of alpha-smooth muscle actin (α-SMA).The number of TUNEL and α-SMA positive cells was analyzed to explore the effects on corneal haze.The haze grading was compared between groups using Kruskal-Wallis H test.Mean values for each experiment were compared between groups using a one-way analysis of variance and LSD-t test.Spearman rank analysis was used to evaluate the correlation between the haze grading and the expression of TUNEL positive cells and α-SMA.Results The corneas of seventy-two eyes reepithelialized in 6 days after operation.The average epithelium repair time of the AE group was (4.12 ± 0.62) d,the dexamethasone group was (5.25 ±0.78) d,and the excipient group was (4.96 ± 0.73) d.The progression of reepithelialization wassignificantly faster in the AE group than the other two groups (F =14.144,P ＜0.01).The haze appeared in the first week after the PRK in all three groups,increased after 3-4 weeks,and relieved after 8 weeks.The degree of haze was significantly lower in the AE group than the other two groups in the first week (Vs.dexamethasone group,H =3.995,P ＜ 0.05 ; vs.excipient group,H =12.77,P ＜ 0.01),in the 4th week (Vs.dexamethasone group,H =4.468,P ＜ 0.05 ; vs.excipient group,H =9.003,P ＜ 0.01),and 8th week (Vs dexamethasone group,H =4.397,P ＜ 0.05 ; vs.excipient group,H =5.744,P ＜ 0.05) after PRK.The TUNEL-positive cells appeared in the central anterior stroma at the first week after surgery.And the number of TUNEL-positive cells in the AE group was (2.2500 ± 0.3750) cells/HP,the dexamethasone group was (4.5000 ±0.7500) cells/HP,and the excipient group was (7.1250 ±0.9063) cells/HP.The number of TUNEL-positive cells in AE group was less than those in the other two groups (Vs.dexamethasone group,t =4.26,P ＜0.01 ; vs.excipient group,t =8.13,P ＜0.01).The TUNEL-positive cells were only found in the excipient group (2.8750 ± 0.6563)/HP in 4th week after operation.It was significantly different between the dexamethasone group and the excipient group (t =9.01,P ＜ 0.01).There were no significant TUNEL-positive cells in 8th weeks in all three groups.α-SMA-positive cells started to appear apparently at the first week after surgery in the dexamethasone and excipient groups,and the peaks appeared at the 4th week after treatments,and there were still a lot of α-SMA-positive cells in corneal stroma at the 8th week after operation in both groups.On the contrary,there were no significant α-SMA-positive cells in the AE group all the time after surgery.The statistical significant difference can be found between the AE group vs.the dexamethasone and excipient groups in the first week (t =28.62,36.55 ;P ＜0.01),in the4th week (t=30.40,35.96; P ＜0.01),and in the 8th week (t =34.02,38.32; P＜0.01).Spearman rank analysis demonstrated that the formation of haze was proportional to the expression of TUNEL positive cells (r =0.881,P ＜ 0.01) and α-SMA (r =0.710,P ＜ 0.01).Conclusion Amniotic extraction can reduce the formation of haze,which was more effective than 0.1％ dexamethasone.It might release certain factors which were transported into corneal matrix,then affected the healing of epithelial cell by interacting with the corneal cell factors,reducing the cell apoptosis,corneal wound healing response and rebuilding the corneal matrix with less myofibroblast,collagen and scar and finally reduce the formation of haze.

In order to comply with the development trend of network and digitalization of journals and provide high-quality services for authors and readers, the Journal of Chinese Medical Association has developed a remote manuscript management system. The system is designed according to the business requirements of manuscript processing process, editing and processing specification, manuscript review system and management specification of Chinese Medical Association series magazines. It adopts advanced database and network technology, and has strong data processing and analysis ability. The remote manuscript management system will assist authors, editors, reviewer experts, editorial board members, finalization meeting experts, editor-in-chief and other related personnel to handle manuscript business in one, solve the needs of editorial department for manuscript networked process management, and realize various functions of inquiry and performance evaluation. In May 2009, this journal officially launched the remote manuscript management system (log in at http: / /www.cjo-eye.com, click "Magazine and Paper Submission System" or log in to the website of Chinese Medical Association "www.cma.org.cn" and click "Business Center").

Blindness caused by corneal disease has become the second most blinding eye disease in China, and most corneal blind patients can see the light again through corneal transplantation surgery. However, due to the limited source of corneal donors in China, there is a huge gap between the annual corneal transplantation surgery volume and the patient demand. It is the unshirkable task of corneal transplantation surgeons to make full use of limited corneal materials and choose reasonable surgical methods. Recently, the author used femtosecond laser flap making technology to perform lamellar keratoplasty and corneal endothelial transplantation on one donor cornea for two patients with keratopathy, respectively, and achieved ideal results.

A 49-year-old woman came to Beijing Tongren Eye Center of Beijing Tongren Hospital affiliated to Capital Medical University on May 31, 2011 due to redness, pain and visual loss in her left eye for 7 months. The patient was diagnosed with bacterial keratitis in her left eye and fungal keratitis in her left eye in another hospital (fungal hyphae was seen in scraping cytology), and she underwent conjunctival flap covering surgery and iodophor cautery treatment in a local hospital 5 months ago. She was in good health before. Eye examination: visual acuity: 1.0 in the right eye, manual in the left eye. The corrected visual acuity did not improve. No obvious abnormalities were found in the cornea, anterior chamber, iris, lens, vitreous body and fundus of the right eye by slit lamp examination.

The patient was a 6-year-old female who came to the Ophthalmology Center of the Second Affiliated Hospital of Zhejiang University School of Medicine due to poor visual acuity in both eyes since childhood. Cardiac ultrasonography showed a small amount of mitral regurgitation. Ocular examination: the corrected visual acuity of both eyes was 0.3 (±18.00 DS), the intraocular pressure was 14 mmHg (1 mmHg =0.133 kPa) in the right eye, and 16 mmHg in the left eye. The cornea of both eyes was transparent, the anterior chamber was deep clear, the iris trembled, and after dilated pupils, the lens was totally decollated below the vitreous cavity, and the retina was flat; The corneal endothelial cell count was 1393/mm2 in the right eye and 1862/mm2 in the left eye. B-ultrasound examination showed lens dislocation in both eyes.

The patient was a 10-year-old male who came to Shixueliang Eye Hospital in Zhangye City, Gansu Province on October 8, 2012 due to decreased visual acuity in both eyes. The mother had no history of infection during pregnancy, full-term delivery, and no history of intrauterine hypoxia; No history of similar disease in the family; There was no history of other diseases.General physical examination: general condition is good, development is normal, no dactyly deformity.Eye examination: the visual acuity of both eyes was 0.1 in the naked eye.The corrected visual acuity was 0.5 (-3.00 DS) in the right eye and 0.8 (-3.00 DS) in the left eye.

Researches of the correlation between sex hormones and dry eye have been concerned early.Ocular surface inflammation,epithelial apoptosis and anormal expression of tear lipocalin and lipid may be important pathogenetic factors of various types of dry eye,and variedness of sex hormone level may have a certain correlation with these factors.The alteration of structure and function of tear film is the direct reason for dry eye.The change of sex hormone level likely gives influence to tear composition and pathological variation of related ocular surface tissues,then affects the structure and function of tear film,and finally lead to dry eye.Different sex hormones give certain different moderating effects to related ocular surface organization,so the recent correlational study of sex hormones and dry eye can be summarized in terms of androgen and estrogen,as these two sex hormones have certain impacts on tear composition and ocular surface organization respectively.

The incidence of diabetes mellitus and its complications,including diabetic keratopathy,was significantly elevated with the improved living standards in China recently.Diabetic keratopathy mainly exhibited several clinical features,including the delay of corneal epithelial regeneration,the decreasing of corneal sensitivity,neurotrophic corneal ulcers.The features were mainly caused by the changes of corneal epithelial basement membrane compositions,glycation products deposition,corneal nerve ending damage,reduced tear secretion and oxidative stress in the hyperglycemic conditions.This review focuses on the progress of molecular and cellular mechanism related with the clinical features,and discusses the main problems in the basic research of diabetic keratopathy.

In 1977, Wiesel and Raviola [] observed an animal model of shape deprivation myopia in young monkeys, and found that without the stimulation of clear object image, it is possible to promote the growth of the axis of the developing eyeball and form myopia. At the same time, a large number of studies have found that there is feedback regulation of optical defocus in the eyeball, which established an experimental model of optical defocus myopia [2-4].

In order to use the terminology and its abbreviations in this field more conveniently and concisely, this journal specifically publishes some foreign language abbreviations which are well-known and recognized. Authors can directly use the following abbreviations in the abstract and text without giving their full names when writing articles. For terms not published, please write the full name in Chinese when they first appear, and write the full name in foreign language and its abbreviations in parentheses, such as: Human Genome Project (HGP).

Chinese Journal of Ophthalmology was founded in 1950. Over the past 60 years, it has recorded the development of ophthalmology in New China, and has become an important part of China's ophthalmology. Up to now, it has become a fine journal that represents the national level externally and guides the academic development internally.

If the topic involved in the thesis is a national or ministerial or provincial fund or key project, the name of the fund project should be indicated with "Fund Project:" as the logo at the beginning of the article, and the project number should be indicated in parentheses. The name of the fund project shall be filled in according to the official name stipulated by the relevant departments of the state, and a number of funds shall be listed in turn, separated by ";". All fund projects must be accompanied by copies of certificates.

It is co-sponsored by Ophthalmology Branch of Shanghai Medical Association, Ophthalmology Branch of National Ten Provincial Medical Associations, Eye, Ear, Nose and Throat Hospital affiliated to Fudan University, College of Optometry of Wenzhou Medical University and China International Science and Technology Conference Center of China Association for Science and Technology; The 14th International Conference on Ophthalmology and Optometry jointly organized by Eye, Ear, Nose and Throat Hospital affiliated to Fudan University, China International Science and Technology Conference Center and Shanghai Ruiou Exhibition Service Co., Ltd. will be held at Shanghai Transnational Procurement Exhibition Center (No.35 Zhongjiang Road, Putuo District, Shanghai) from March 27th to 30th, 2014.

Chinese Journal of Ophthalmology is a professional academic journal of ophthalmology sponsored by Chinese Medical Association. It targets ophthalmologists as the main readers, reporting leading scientific research achievements, clinical diagnosis and treatment experience in the field of ophthalmology, and basic theoretical research that has a guiding role in ophthalmology clinics and is closely integrated with ophthalmology clinics. The purpose of this journal is to implement the principles and policies of the Party and the state on health work, implement the principle of combining theory with practice, popularization and improvement, reflect the significant progress of clinical and scientific research in ophthalmology in China, and promote academic exchanges in ophthalmology at home and abroad.