Volume 93 · Issue 08 · 1980

In 200 autopsies of stroke cases, there were 99 cerebral hemorrhages including hypertensive cerebral hemorrhage 78, cerebral blood vessel anomalies 7, anemia 5, leukemia 4, tuberculous meningitis 2, septicemic, cerebral hemorrhage 1, severe jaundice complicated by cerebral hemorrhage 1 and posttraumatic subdural hemorrhage 1. There were 53 cerebral infarctions in which there were cerebral embolisms 48, cerebral thrombosis 4 and cerebral venous thrombosis 1. There were also hypertensive encephalopathy 15, cerebral tumors 33 including primary brain tumors complicated by hemorrhage 2, metastatic choriocarcinoma 25 and other matastatic carcinomas 6. According to our autopsies cerebral hemorrhage is the most frequent cause of stroke with cerebral embolism ranking second while cerebral thrombosis is much less important. Cerebral atherosclerosis developed progressively over a very long course and it does not trigger strokes if it is without complications.

Optic disc vasculitis may be of 2 different types, hence the fundus may show either marked edema of the optic disc or signs of central retinal vein obstruction without other ocular or systemic abnormality. 42 cases of this disease (51 eyes) are presented and analysed in this paper.

Measurement of progesterone levels in peripheral plasma during normal human menstrual cycles and pregnancy by competitive protein binding assay shows that during the follicular phase mean plasma progesterone concentrations are 0.39±0.14 ng/ml. Its maximal value during the luteal phase is 8.9±1.87 ng/ml. On the day before or on the first day of menstruation the level falls to 1.79±1.21 ng/ml. In early pregnancy the progesterone concentrations are similar to those during the luteal phase. Thereafter it rises gradually and peaks during late pregnancy, the maximal value being over 130 ng/ml. Anordrin can decrease plasma progesterone levels and shorten the luteal periods of treated women. AF-75 shows no ovulation or development conspicuous effect on of the corpus luteum.

This paper reports observations on 4,321 fertible women using the flower intrauterine device (IUD) from 1965-1977. The material was collected from 13 hospitals in Guangdong province.

Both cases studied presented with typical hairy cells and splenomegaly, establishing hairy cell leukemia (HCL) diagnosis. When white cell count is high, hairy cell percentage is also high. Case 1 with unique leukocytosis, unimproved by splenectomy and prednisone plus vincristine, showed improvement on leukerancyclophosphamide therapy. Hairy cells are probably lymphocyte-monocyte hybrids, but both of our cases conform to B lymphocyte. Pseudosinuses in the spleen are helpful to HCL diagnosis. Ribosome lamellar complexes and tartarate resistant acid phosphatase reaction are also helpful to the diagnosis but neither is HCL specific.

Large scale control of malayan filariasis has been achieved in China by carrying out mass surveys and total population treatment mainly with diethylcarbamazine (DEC) or DEC medicated salt reducing the microfilaria rate to minimum levels. But surveillance and campaigns must be continued for at least 10 years. We have little experience in exterminating the Anopheles sinensis vector. The density of this species of vector is still fairly high here so further investigation and studies should be made in order to find a method of controlling it. This is our major task today.

A quantitative histologic method of pancreatic islet measurement is used in the analysis of hypoglycemic cases in order to find a basis for differentiating islet hyperplasia from insulinoma. Analysis of the results of measuring 20 normal control patients, 11 insulinoma patients and 6 hypoglycemic but exploration negative patients reveals that islet hyperplasia in the distal pancreas resected during exploration of hypoglycemic patients is an important criteria for differential diagnosis of islet hyperplasia from insulinoma. The methods of calculation and analysis are described and several aspects of quantitative analysis and differential diagnosis between islet hyperplasia and insulinoma are discussed.

A simple method of culturing amniotic fluid cells for detection of fetal chromosome abnormalities and genetic diseases is presented. 26 cases were studied by this method with a 92% success rate.

The counterimmunoelectrophoresis (CIEP) technic is a rapid and accurate immunodiagnostic test for detecting paragonimiasis. 57 cases of paragonimiasis were examined by this method and all showed positive reactions. For comparison, their sera were also examined by agar gel diffusion (AGD) test. It was noted that the number of positive reactions obtained by AGD was 63% that by CIEP. The average CIEP titer was 13 times higher than the AGD. Only 1 (0.4%) of the 275 controls showed a false positive reaction by CIEP and no false positive was obtained by AGD. Follow-up observations on 34 cases were made after treatment. It was found that the majority of the cases (29/34, 85.3%) had negative CIEP reactions at 6 months or a little more after treatment.