2013年 · 第51卷第01期

In this journal, the paper "Quality Evaluation of Therapeutic Research Literature Published in Chinese Journal of Pediatrics" written by Wang Yulin and others published in this journal, through relatively sufficient investigation and research, it is concluded that the quality of clinical research treatises published in this journal in the past six years is not high, and there are still many shortcomings according to the internationally prevailing and generally accepted and recognized reporting guidelines for randomized controlled clinical studies CONSORT. In order to improve the level of clinical research in pediatric medicine in China, it is necessary for us to understand: (1) What is the CONSORT guideline? (2) What are the main points of the CONSORT Guide? (3) Do we need to familiarize ourselves with and master these guidelines? Why? (4) What are the consequences of not being familiar with these guidelines and not implementing their requirements? Wait.

The 4-month-old male patient was seen for more than 1 month mainly due to unstable head control. One month ago, parents found that the child gradually couldn't raise his head and could stare, but couldn't trace, was insensitive to sound reaction, and was easy to cry and provoke. When crying, his body was strong and his head leaned back, and occasionally his lower limbs shook spastically. Poor milk feeding, normal urine and defecation.

The 2-month-old child was admitted to the hospital with "phlegm for 7 days, fever and asthma for 5 days". Shortly after birth (details unknown), phlegm appeared repeatedly, accompanied by shortness of breath, which could be improved by local treatment. Phlegm appeared again 7 days before admission, accompanied by mouth spitting foam, no obvious cough, no asthma and cyanosis. Fever began 5 days before admission, with a maximum body temperature of 39.4℃, accompanied by asthma. He was diagnosed with "pneumonia" in another hospital, and was successively treated with "cefotaxime, mexicillin sodium sulbactam", "methylprednisolone" and "ambroxol hydrochloride". The child's body temperature dropped and then rose again. Phlegm and asthma did not improve significantly, but aggravated, accompanied by perioral cyanosis, and was transferred to our hospital. Admission physical examination: T38.8℃, conscious, flat and soft anterior fontanel, no cyanosis on the face and perioral area, shortness of breath, 85 beats/min, flapping of the nose, positive triple concave sign, dense small blister sounds and dry rales can be heard in both lungs, heart rate 188 beats/min, uniform rhythm, low and dull heart sounds, no murmur. The liver was not swollen under the costs, the extremities were warm, and no purple patterns were seen. After admission, he was given "melocillin sodium sulbactam" for anti-infection, aerosolization to relieve asthma, sputum suction and oxygen inhalation. Blood routine: white blood cells 13.80 10^－9/L, neutrophil ratio 59.50%, hemoglobin 86 g/L, total platelet count 744 10^－9/L, mycoplasma and chlamydia IgM negative, liver and kidney function normal. CRP 21.000 mg/L. Chest X-ray on admission showed pneumonia. The child's breathing was still rapid under oxygen administration with a hood, and he choked and coughed when feeding with milk powder, and it was difficult to insert a gastric tube. Esophagotracheal fistula was suspected. Esophagotracheal fistula was highly suspected after bedside lipiodol angiography. Compared with 2 chest radiographs, esophageal T₁A round foreign body shadow was found horizontally, and a foreign body was suspected. Emergency chest CT showed a foreign body in the esophagus. After obtaining the consent of the family, a button battery was taken out through a gastroscope under general anesthesia in the operating room, which was rusty. The diameter of the foreign body is about 2 min, and the foreign body removal process is smooth. After the foreign body was removed, gastroscopy showed an esophagotracheal fistula with a large fistula. Five minutes after the foreign body was removed, the heart rate suddenly dropped, accompanied by cyanosis and abdominal swelling, and he died after ineffective rescue. Diagnosis of death: esophageal foreign body with esophagotracheal fistula.

tic disorders (TD) are neuropsychiatric disorders that begin in childhood and have tic as the main clinical manifestation^[1,2]。 Its pathogenesis is the result of the interaction of genetic, biological, psychological and environmental factors. The exact etiology and pathogenesis are unclear, the imbalance of central neurotransmitters, striatal dopamine hyperactivity or postsynaptic dopamine receptor hypersensitivity are the key links of its pathogenesis^[1,3]。 The incidence of TD has been increasing in recent years. Its clinical manifestations are diverse, and its comorbidities are complex. The diagnosis and treatment need to be standardized.

The 16th National Academic Conference on Pediatric Hematology, co-sponsored by the Hematology Group of the Pediatrics Branch of the Chinese Medical Association and the Editorial Committee of the Chinese Journal of Pediatrics, was held in Huangshan City, Anhui Province on June 28-29, 2012. More than 300 representatives from all provinces, municipalities and autonomous regions attended the meeting. The conference received a total of 304 manuscripts, including 7 special lectures, 7 special speeches and 36 speeches at the conference. This conference continued with the opening of a youth forum, and for the first time added a discussion of difficult cases. The atmosphere at the meeting was lively, and the participants expressed their opinions, shared and exchanged clinical and scientific research achievements in recent years.