2025年 · 第48卷第03期

Every month is always fleeting, and in the blink of an eye, it is the spring season again. This magazine will meet with you in the third issue of 2025.

The European Chronic Thromboembolic Pulmonary Hypertension Registry (CTEPH) report, conducted between 2007 and 2012, found that pulmonary endarterectomy (PEA) has a significant impact on the long-term survival of patients with CTEPH. Since then, there have been 2 more inoperable treatments for CTEPH: balloon pulmonary angioplasty (BPA) and an approved oral drug therapy, the guanylate cyclase agonist riociguat. This registry aims to evaluate the long-term effects of these new treatments worldwide.

The role of serotonin in pulmonary hypertension has been a hot spot in clinical research in recent decades, and preclinical research data strongly indicate its involvement in the pathogenesis of disease; However, many clinical studies have yielded different results.