2021年 · 第101卷第35期

The health impact, social impact and stigma caused by the novel coronavirus pneumonia (COVID-19) pandemic make COVID-19 patients more prone to mental and psychological problems such as anxiety and depression. As a result, Taquet et al. used the TriNetX analytics network to capture anonymous data on 69.8 million patients from the electronic health records of 54 U.S. healthcare organizations, including 62,354 patients diagnosed with COVID-19 between January 20 and August 1, 2020. Create a cohort of patients diagnosed with COVID-19 or a range of other health events, use propensity score matching to control for confounding bias in COVID-19 risk factors and disease severity, measure the incidence and hazard ratios of mental disorders, dementia, and insomnia within 14 to 90 days after COVID-19 diagnosis (HR), to assess the association of reporting COVID-19 with mental illness. The results showed that compared with influenza, other respiratory infections and other diseases, the diagnosis rate of mental illness increased by about one time. Psychiatric disorder was diagnosed for the first time in 5.8% (3 627/62 354), anxiety disorder in 4.7% (2 931/62 354), and mood disorder in 2.0% (1 247/62 354). Furthermore, the incidence of the first diagnosis of dementia within 14 to 90 days after being diagnosed with COVID-19 was 1.6% (998/62 354) in people over 65 years of age. The study suggests that the mental health of COVID-19 patients after discharge should not be ignored. The long-term follow-up study of COVID-19 can help to understand the physical, psychological and social outcomes of COVID-19, and provide early intervention for specific groups to improve the level of medical care and quality of life of patients. At present, the maximum discharge time for COVID-19 patients is about 1 year, and continued follow-up is required to clarify the long-term prognosis of COVID-19.