Helicobacter pylori (H. pylori) Infection is an important risk factor for gastric cancer, and eradicationH. pyloriCan effectively prevent the occurrence of gastric cancer. The latest major guidelines and consensus at home and abroad clearly state that:H. pyloriInfection is an infectious disease, and all infected people should be given eradication treatment. However, due to the irregular use of antimicrobial drugs,H. pyloriThe rate of resistance to commonly used antimicrobial drugs increased year by year, and the success rate of eradication decreased year by year. In almost all member countries of the six regions of the World Health Organization (WHO),H. pyloriResistance rates to clarithromycin, metronidazole and levofloxacin have all exceeded 15 percent, resulting in the "standard triple regimen" based on the above three antimicrobials no longer being suitable for eradicationH. pyloriEmpirical treatment protocols of. Therefore, there is an urgent need to develop new and safe and effectiveH. pyloriTherapeutic options for eradication.
