1984年 · 第97卷第11期

A new set of picture vision test cards for the Chinese preschool children is designed on the principle of the SneUen chart. There is a significant correlation between the test results by our test cards and by the conventional E chart (r=0.9840, p<0.01). These test cards are recommended for the Chinese preschool children who cannot grasp the idea of the conventional E chart or refuse to cooperate in tests with such a chart.

Echocardiography was performed in 106 children of Keshan disease and 150 healthy children served as control. Dilatation of cardiac cavities and impairment of ventricular function were observed in all types of Keshan disease in this series. The percentage of left ventricular segmental asynergy was relatively high in children (31.1%) and this was usually associated with electrocardiographic abnormal Q wave or ST-T change. Therefore, the value of the commonly used parameters of cardiac function such as SV, EF, ΔD% and VCF is limited. Since the measurement of EPSS and the B shoulder formation are not affected, they can be used as practical screening parameters for the measurement of cardiac function of children with Keshan disease. The marked decrease of contraction of the lower part of the left ventricle and the left ventricular segmental asynergy may be helpful in the differential diagnosis of Keshan disease from other cardiomyopathies. However, further investigation is needed.

In the early period of repair following a standardized fracture of the radius of rabbits, capillary formation can be seen in five different callus regions. The capillaries may be formed from a single endothelial cell, or conjointly by two or more endothelial cells. When the endothelial cells contacted with each other, the cell membranes may be intimately joined together or form a cleft to facilitate the passage of water, while in some cases a membranous flap may be formed, extending into the capillary lumen. There are pericytes surrounding and abutting on the capillaries. Both capillaries and pericytes are invested by a basal lamina.

In the course of healing of standardized radius fracture in rabbits, there is emergence of extracellular matrix vesicles with subsequent calcification prior to the deposition of calcium salts in the collagen fibrils. The calcified matrix vesicles turn into flocculent calcospherules which coalesce to form bone substance. The phenomenon of calcification of matrix vesicles takes place not only around the osteoblasts and chondrocytes but also around the fibroblasts. The same sequential events about changes in matrix vesicle can be detected whether the fibroblasts are in an active secreting state, and transform into osteocytes, or undergo degeneration, decease, and replacement by bone substance. Because deposition of calcium salt crystals takes place in the collagen fibrils abutting the fibroblasts and the fibroblasts transform into osteocytes, the findings in our study show the importance of fibroblasts in osteogenesis in the course of fracture healing.

In this paper we report preliminary results of clinical trials in which 2 patients with gliomas of the brain were treated with a combination of surgery and microwave hyperthermia using invasive techniques, with a follow-up of more than one year. The method of treatment is discussed and the equipment, consisting of a 2.45 GHZ microwave genera tor and the antenna system, is described.

We surveyed antibiotic resistant and various bioactive Escherichia coli strains isolated in the Capital Hospital in Beijing in 1981. It was found that most of the clinical strains in Beijing were antibiotic resistant. Tetracycline resistant strains were most prevalent (92%), and incidences of resistant strains to streptomycin, sulfonamides, chloramphenicol, ampicillin and kanamycin decreased in this order, suggesting that tetracycline derivatives were widely used in Beijing. Incidence of conjugative R plasmids in Beiijng (38%) was same as that in Tokyo and lower than that in Moscow. We examined hemagglutination, the common antigens with small intestine adhesive bacteria, colicin production, enterotoxin production, DNase production, invading ability into intestinal epithelial cells, active iron incorporating ability and capsules of the collected strains and found that incidences of these bioactive strains were not so different from those in Tokyo, although minor differences were found in many characters. None of the genes for these bioactive characters were found on the highly conjugative plasmids. This lower incidences of bioactive as well as conjugative R plasmids in Beiijng and Tokyo than those in Moscow suggested that plasmids in E coli strains in Beijing were similar to those in Tokyo but different from those in Moscow.

We observed ultrastructurally the terminal villi of 10 pre-eclamptic placentas and found that the proliferation of cytotrophoblast cells is closely related to the local circulatory disturbance and probably is a kind of compensatory process. Fibrinoid deposition in the villus is a process of fibrinoid degeneration, to which the thickening of subtrophoblast lamina would be related. Variation of the cytotrophoblast cells and stroma cells of the villus showed configurations similar to those of the decidual cells. The formation of fibrinoid material possibly due to the degenerative changes in the two types of cells is discussed.

The SGC-7901 gastric adenocarcinoma cell line is established. It is cultured from material obtained from metastasized lymph nodes on the gastric lesser curvature in a female patient. The cell line re produces continuously every 7 days. Polygonal and epithelioid cells account for 95.2% of the cell population. There is marked poikilocytosis. The chromosome modal number is 67, constituting 42% of the karyotyped cells. Chromosome aberration is observed in 6% of the cases. Percentage of secondary tumor growth is high by animal inoculation. Both the cultured cells and those of the primary tumor were PAS positive and Accian blue negative. Transmission electron microscopy (TEM) revealed microvilli over the cell surface and intracellular secretory granules; multiple intercellular junctional and inlay structures were also demonstrated.

Amniotic fluid analysis involving 119 tapings was performed in 95 high risk pregnancy patients from March 1980 to October 1981. This is, at present, the most accurate method for assessing fetal maturity. The accuracy of the L/S ratio, foam test and creatine value was 96.98%, 94.89% and 86.6%, respectively. The study shows that amniotic fluid analysis plays an essential role in the planned delivery of high risk pregnancies. Intra-amniotic administration of dexamethasone can promote fetal maturity and is also very important in the management of the condition.