MedNexus
2016年 · 第19卷第05期
出版日期 2016-10-01电子版 ¥0.00元
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Invited Review
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精准医疗的定义与应用Zheng-Guo Wang, Liang Zhang, Wen-Jun Zhao
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.04.005
摘要
2011年,美国四大研究机构——科学院、国家工程院、国家卫生研究院和国家科学基金会发布了精准医疗联合研究计划。2015年1月,奥巴马总统在国情咨文中宣布了一项关于精准医学研究的提案,旨在治愈和接近治愈癌症、糖尿病等疾病,并获得个人和家庭可能需要的医疗记录。
Original Article
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死冠的新概念、新分类及其临床意义Talalwah Waseem Al
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.004
摘要
Purpose:
The obturator artery and its accessory (aberrant) arising from different origins and crossing the pubic rami are vascular variations. The internal iliac artery usually provides the obturator artery which may communicates with the external iliac artery through either the accessory obturator or inferior epigastric artery. A collateral circulation between the external and internal iliac system is known as corona mortis. The aim of current study is to provide sufficient data of vascular variability crossing the pubic rami for clinical field.
Methods:
Present study includes 208 hemipelvises dissected in the Institution of Anatomy, Medical University of Graz. During dissection, the obturator artery and its accessory crossing the superior rami of pubic bone were found to have different origins.
Results:
The obturator artery arising from the external iliac artery and from the femoral artery accounts for 9.8% and 1.1% respectively. Therefore, it passes over the superior pubic rami in 10.9%. Further, the accessory (aberrant) artery arises only from the femoral artery in 1.1%. In present study, the vascular variation crossing the superior pubic rami with or without collateral circulation between external and internal iliac system referred as corona mortis is addressed. This study includes new classification of obturator and accessory obturator arteries as well as the corona mortis. It includes a comparison of corona mortis incidence in Austria population and other populations. The corona mortis found to be in 12% of Austrian population.
Conclusion:
A great attention of clinicians, radiologists, surgeons, orthopedic surgeons, obstetricians and gynecologists has to be considered before pubic surgical procedures such as internal fixation of pubic fracture, an inguinal hernia repair. Further, traumatic pubic rami fracture may lead to massive hemorrhage due to laceration of the obturator artery.
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髌骨横向骨折张力带固定术的生物力学分析Mohammed Ali, Jan Kuiper, Joby John
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.009
摘要
Purpose:
Tension band wiring is commonly used for fixation of simple transverse fractures. The popular configuration is parallel Kirschner wires (K-wires) and a stainless steel wire loop placed in a vertically oriented figure-of-8.
Methods:
We used a wooden model of a patella with a midway transverse fracture and compared four different types of fixation. The first construct had a vertical figure-of-8 with one twist of wire. The second contained a vertical figure-of-8 with two twists of wire. The third was a vertical figure-of-8 with two twists of wire placed at adjacent corners while the last one had a horizontal figure-of-8 with two twists of wire placed at adjacent corners. Interfragmentary compression at the point of wire breakage was measured for each construct as well as permanent displacement on cyclic loading.
Results:
Placement of the figure-of-eight in a horizontal orientation with two wire twists at the corner improved interfragmentary compression by 63% (p < 0.05, Tukey post hoc test). On cyclic loading, all the constructs with vertical figure-of-eight but none with a horizontal construct failed (p = 0.01; Fisher's exact test). Permanent fracture displacement after cyclic loading was 67% lower with horizontal figure-of-eight constructs (p < 0.05; t test).
Conclusion:
Placing wire twists at the corner and a horizontal placement of figure-of-8 improves stability of the construct.
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唑来膦酸注射联合股骨近端钉抗旋治疗骨质疏松性股骨粗隆间骨折Yong Li, Wen-Bo Zhao, De-Li Wang, Qing He, Qin Li, Fu-Xing Pei, Lei Liu
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.07.001
摘要
Objective:
To observe the clinical results of proximal femoral nail anti-rotation (PFNA) combined with zoledronic acid injection in the treatment of osteoporotic intertrochanteric fractures in the elderly.
Methods:
60 elderly patients with osteoporotic intertrochanteric fractures were diagnosed using a dual energy X-ray bone density instrument. Patients were randomly divided into treatment or control groups (30 cases in each group). Patients in both groups were treated by closed/open reduction and internal fixation using PFNA. In the treatment group, patients received one zoledronic phosphonic acid injection of 5 mg/100 ml via intravenous drip, in addition to 600 mg of Caltrate D (qd) and 0.25 μg of alpha ossification alcohol (qd). The control group received 600 mg of Caltrate D (qd) and 0.25 μg of alpha ossification alcohol (qd). The oral drugs were administered for 12 months. Bone pain relief was observed, and changes in the bone mineral density (BMD) of the lumbar and health-side hip were recorded. Clinical results were evaluated using the Visual Analogue Scale (VAS), Harris joint function score, and Osteoporosis Quality of Life Scale (OQOLS).
Results:
Compared with the control group, bone pain symptoms were significantly alleviated (p < 0.05) in the treatment group. In the treatment and control groups, both between-group and within-group differences in BMD were significantly increased in L1-4, femoral neck and trochanter (p < 0.05). No significant differences were found between the two groups in regard to the involved hip or the total rate of improvement at the end of the follow-up period, although cases in the treatment group had higher OQOLS scores than those of the controls (p = 0.04). Cases in the treatment group healed more quickly than those in the control group [(13 ± 3.2) weeks vs (15 ± 4.6) weeks, p = 0.02]. During the follow-up period, cases in the treatment group had no new fractures, whereas 2 new cases of hip fracture and 2 cases of distal radial fractures were observed among the controls.
Conclusion:
Zoledronic acid injection combined with PFNA is a favorable treatment option for the elderly patients with osteoporotic intertrochanteric fracture. It can effectively relieve bone pain, increase bone density, improve quality of life, reduce the occurrence of new fractures and promote fracture healing.
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伊朗暴力领域研究人员的社会网络分析Payman Salamati, Faramarz Soheili
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.008
摘要
Purpose:
The social network analysis (SNA) is a paradigm for analyzing structural patterns in social relations, testing knowledge sharing process and identifying bottlenecks of information flow. The purpose of this study was to determine the status of research in the field of violence in Iran using SNA.
Methods:
Research population included all the papers with at least one Iranian affiliation published in violence field indexed in SCIE, PubMed and Scopus databases. The co-word maps, co-authorship network and structural holes were drawn using related software. In the next step, the active authors and some measures of our network including degree centrality (DC), closeness, eigenvector, betweeness, density, diameter, compactness and size of the main component were assessed. Likewise, the trend of the published articles was evaluated based on the number of documents and their citations from 1972 to 2014.
Results:
Five hundred and seventy one records were obtained. The five main clusters and hot spots were mental health, violence, war, psychiatric disorders and suicide. The co-authorship network was complex, tangled and scale free. The top nine authors with cut point role and top ten active authors were identified. The mean (standard deviation) of normalized DC, closeness, eigenvector and betweeness were 0.449 (0.805), 0.609 (0.214), 2.373 (7.353) and 0.338 (1.122), respectively. The density, diameter and mean compactness of our co-authorship network were 0.0494, 3.955 and 0.125, respectively. The main component consisted of 216 nodes that formed 17% of total size of the network. Both the number of the documents and their citations has increased in the field of violence in the recent years.
Conclusion:
Although the number of the documents has recently increased in the field of violence, the information flow is slow and there are not many relations among the authors in the network. However, the active authors have ability to influence the flow of knowledge within the network.
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创伤性脑损伤与卒中认知特征的差异:蒙特利尔认知评估与简易精神状态检查的比较Hao Zhang, Xiao-Nian Zhang, Hui-Li Zhang, Liang Huang, Qian-Qian Chi, Xin Zhang, Xiao-Ping Yun
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2015.03.007
摘要
Purpose:
To investigate the profiles of cognitive impairment through Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) in patients with chronic traumatic brain injury (TBI) or stroke and to evaluate the sensitivity of the two scales in patients with TBI.
Methods:
In this cohort study, a total of 230 patients were evaluated, including TBI group (n = 103) and stroke group (n = 127). The cognitive functions of two groups were evaluated by designated specialists using MoCA (Beijing version) and MMSE (Chinese version).
Results:
Compared with the patients with stroke, the patients with TBI received significantly lower score in orientation subtest and recall subtest in both tests. MoCA abnormal rates in the TBI group and stroke group were 94.17% and 86.61% respectively, while MMSE abnormal rates were 69.90% and 57.48%, respectively. In the TBI group, 87.10% patients with normal MMSE score had abnormal MoCA score and in the stroke group, about 70.37% patients with normal MMSE score had abnormal MoCA score. The diagnostic consistency of two scales in the TBI group and the stroke group were 72% and 69%, respectively.
Conclusion:
In our rehabilitation center, patients with TBI may have more extensive and severe cognitive impairments than patients with stroke, prominently in orientation and recall domain. In screening post-TBI cognitive impairment, MoCA tends to be more sensitive than MMSE.
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血清钙与不同类型的髋部骨折有关吗?回顾性研究Peng-Fei Li, Zi-Ling Lin, Zhi-Hui Pang, Yi-Rong Zeng
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.003
摘要
Purpose:
To investigate the potential correlation between two different types of hip fractures and serum calcium levels.
Methods:
We consecutively studied 101 cases of femoral neck fracture and 95 cases of femoral intertrochanteric fracture between January 2011 and December 2013. Fasting blood samples were taken and serum calcium measurements were performed respectively in three periods: the time of admission, postoperation, and discharge. Creatinine, alkaline phosphatase and albumin were also analyzed.
Results:
Considering the levels of serum calcium between two groups at the time of admission, post-operation and discharge, there was significant difference at admission and discharge (p < 0.05), while there was no significant difference at the time of postoperation (p > 0.05). The magnitude of serum calcium fluctuation was larger in femoral neck group than femoral intertrochanteric group. Concerning alkaline phosphatase and albumin levels at admission, there was no significant difference between two groups (p > 0.05).
Conclusion:
The capability of reservation and restoration of serum calcium in patients with femoral neck fracture is better than that in patients with femoral intertrochanteric fracture. A low serum calcium level may be susceptible to femoral intertrochanteric fracture.
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外固定与切开复位内固定治疗胫骨pilon骨折的比较:一项基于观察性研究的荟萃分析Yi-Chen Meng, Xu-Hui Zhou
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.002
摘要
Purpose:
Tibial pilon fractures remain challenging for an orthopaedic surgeon to repair. External fixation (ExFix) and open reduction and internal fixation (ORIF) are two widely used methods for repairing tibial pilon fractures. However, conclusions of comparative studies regarding which method is superior are controversial. Our aim is to compare ORIF and ExFix and clarify which method is better in terms of reduction and union results and major complications.
Methods:
A computerized research of MEDLINE, EMBASE, Springer, and Cochrane Library (before December 2014) for studies of any design comparing ORIF and ExFix was conducted. Weighted mean difference (WMD), risk ratio (RR) and corresponding 95% confidence intervals (CI) were used for estimating the effects of the two methods. Statistical analyses were done using Review Manager Version 5.2.
Results:
Ten cohort studies and one randomized clinical trial were included in our ultimate analysis. And the analysis found no significant difference between the two methods in deep infection (p = 0.13), reduction (p = 0.11), clinical evaluation (p = 0.82), post-traumatic arthrosis (p = 0.87), and union time (p = 0.35). Besides, ExFix group was found to have a higher rate of superficial infection (p = 0.001), malunion (p = 0.01) and nonunion (p = 0.02), but have a lower risk of unplanned hardware removal (p = 0.0002).
Conclusions:
We suggest that ORIF has a relatively lower incidence rate of superficial infection, malunion and nonunion, but a higher rate of unplanned hardware removal. No difference was found in deep infection, reduction, clinical evaluation, post-traumatic arthrosis and union time.
Case Report
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股骨粗隆下骨样骨瘤合并髋部骨折误诊1例N.K. Sferopoulos
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.03.006
摘要
A 34-year-old man with a subtrochanteric osteoid osteoma localized to the lateral cortex of the left femur is reported. The patient presented with mild spontaneous pain of the lateral thigh and knee. He refused a radiographic examination and was treated as a greater trochanteric pain syndrome for 9 months. He was then admitted with a transcervical fracture of the neck of the left femur after a fall from standing height. The fracture was fixed with 3 cannulated screws and healed uneventfully. His symptoms worsened after the first postoperative year. Eighteen months postoperatively the pain was dull, worsening at night, and relieved only with anti-inflammatory drugs, and he had a limp. New radiographs and tomograms were indicative of a lateral subtrochanteric osteoid osteoma with a subperiosteal localization. The lesion was treated successfully with surgical excision of a piece of reactive bone including the nidus.
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年轻女性双侧节段性骨盆和股骨骨折:一例罕见病例报告Raju Vaishya, Amit Kumar Agarwal, Nishint Gupta, Vipul Vijay
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.01.017
摘要
The management of multiple complicated injured patients remains a great challenge despite advancements in modern medical care. We present a rare case of bilateral unstable pelvic fractures associated with bilateral segmental femoral shaft fractures. We have proposed a mechanism of such complex injury pattern and discussed the plan of management. We believe that a timely and aggressive surgical intervention to fix all the major fractures soon after medically stabilizing the patient helped our patient to overcome these serious and lethal injuries. It is necessary to establish an optimal protocol for management of such complex fractures by conducting prospective and multicentric studies in the future.
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跟腱修复术后急性节段性单室综合征的计算机断层血管造影和磁共振成像表现:病例报告和文献复习Jiang Li-Feng, Li Hang, Xin Zeng-Feng, Wu Li-Dong
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.03.005
摘要
Acute compartment syndrome of the lower extremity is a serious postinjury complication that requires emergency treatment. Early diagnosis is of paramount importance for a good outcome. Four muscle compartments in the calf (anterior, lateral, deep posterior, and superficial posterior) may be individually or collectively affected. Acute segmental single-compartment syndrome is an extremely rare condition characterized by high pressure in a single compartment space with threatening of the segmental tissue viability. In this case report, we describe a young man with Achilles tendon rupture who complained of postoperative pain in the anterior tibial region. Emergent computed tomography angiography and magnetic resonance imaging revealed local muscle edema. Segmental anterior compartment syndrome was diagnosed and fasciotomy was performed.
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闭合复位和Latarjet手术治疗6个月大被忽视的肩关节前脱位Deepak Chaudhary, Deepak Joshi, Vineet Jain, Mukul Mohindra, Nitin Mehta
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2016.06.005
摘要
A neglected shoulder dislocation is a rarer entity and only few cases are reported in the literature. An anterior dislocation of the shoulder is rarely missed as patients present with limb in abduction and external rotation, an attitude very familiar to orthopaedic surgeon. Occasionally such cases are missed when they present with fracture of proximal humerus or when they receive treatment from unqualified practitioners who commonly practise in rural areas. Owing to very few reports there is paucity of literature and no standard treatment protocol exists for neglected anterior dislocation of the shoulder, though most such chronic cases are managed by open reduction. This case report describes a six months old neglected anterior dislocation with a significant Hill Sachs lesion, which was managed by closed reduction and Latarjet procedure.
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锁定钢板联合腓骨髓内移植治疗重度骨质疏松症肱骨骨折不愈合Shabir Ahmed Dhar, Mohammed Farooq Butt, Tahir Ahmed Dar, Reyaz Ahmed Dar, Zameer Ali
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2015.11.020
摘要
Nonunion of the humerus in a severely osteoporotic bone is a likely event especially if the fracture is transverse. The management of such a combination is a challenge. Most of the conventional fixation methods are unlikely to succeed as the bone failure precedes implant failure in osteoporosis. The challenge is further compounded in severe osteoporosis when the cortical thickness is affected more severely. We used a combination of an intramedullary fibula with a locking plate in 5 cases. The results show that it may be a good combination in such situations as the bone strength is augmented and the plate pullout is less likely.
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全腹腔镜下腹膜游离皮瓣修复手部En-Qi Guo, Qing-Ping Xie
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2015.12.014
摘要
Management of defects on the hand and foot with exposed tendons remains a major challenge for plastic surgeons. Here, we present a case of hand reconstruction with a totally laparoscopic peritoneal flap. The anterior rectus sheath was preserved in situ. The peritoneal free flap supplied by peritoneal branches of the deep inferior epigastric artery was retrieved by laparoscopy to cover the soft tissue defect of the hand. The defect of the dorsal hand was 17 cm × 12 cm. The peritoneal flap measuring 22 cm × 15 cm survived completely without any complications. A following split-thickness skin graft offered the successful wound closure. Motor and sensory function improved gradually within the first year follow-up. The totally laparoscopic peritoneal free flap is a good choice for reconstruction of the soft tissue defects accompanied by exposed tendons on the hand and foot.
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肱骨近端骨折部位克氏针移位,导致水气胸Balaji Zacharia, Kishor Puthezhath, Ibin Varghees
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2015.12.010
摘要
Migration of wires or pins around the shoulder is a known complication, though their migration within the chest is uncommon. We report an unusual case of hydropneumothorax due to migration of a bent Kirschner wire from the right proximal humerus in a 63 year-old man. We reviewed his clinical history, physical examination, imaging findings, surgical method and outcome. We also reviewed the literature on orthopaedic wire migration and latest technique in removal of the wires. Chest radiographs and chest computerized tomography are useful in detection and diagnosis of this disorder. Regular radiographic follow-up is needed for patients with internal fixation devices; any fractured or migrated pins or wires must be removed immediately to prevent dangerous complications. It is always important to remove the wires at the end of the treatment. Early removal of fixation wires and regular follow-up if wires are retained are essential to prevent serious complications.
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大腿前外侧游离皮瓣同时重建指伸肌腱及手背缺损1例Man-Yi Cui, Hui Shen
中华创伤杂志英文版2016年 19卷 05期
DOI: 10.1016/j.cjtee.2015.11.019
摘要
This paper describes a new technique in the repair of the hand defect with digital extensor tendon injury. The anterolateral thigh flap with the thick femoral fascia has been used in the reconstruction of the composite defect of the dorsal hand, especially the defect of tendon. This technique requires short period of treatment and hence causes less damage to the donor site but shows a better recovery of the hand function. A favorable curative effect has been obtained in this patient.
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