2015年 · 第35卷第10期

Digestive system diseases often affect the digestive and absorption function of patients, so patients are more likely to combine nutritional problems. Nutritional risk refers to the risk that nutritional factors negatively affect a patient's clinical outcome, such as complications, length of stay, hospitalization costs, etc., rather than the risk of undernutrition^[1]。 At present, there are many nutritional assessment standards, and there is a lack of uniform assessment tools for hospitalized patients. This study selected the nutritional risk screening tool recommended by the European Society for Parenteral Enteral Nutrition in 2002, namely the Nutritional Risk Screening 2002 (nutritional risk screening 2002, NRS-2002)^[2]To evaluate the nutritional status of patients admitted to gastroenterology department, and investigate their nutritional risks, the incidence of nutritional deficiency and the application status of nutritional support at discharge, so as to provide a basis for the rational application of nutritional support in gastroenterology inpatients.

Clinically, extrahepatic bile duct stones do not necessarily cause bile duct dilation. Danyang People's Hospital treated 112 patients with gallbladder stones combined with extrahepatic bile duct stones found during laparoscopic cholecystectomy (LC). Ureteral catheter was placed through the cystic duct for biliary drainage, and endoscopic lithotomy was performed within 4 days after operation to treat non-dilated extrahepatic bile duct stones, and good results were achieved. The effectiveness and safety are analyzed as follows.

The staging of liver fibrosis is closely related to its treatment and prognosis. At present, pathological examination of liver biopsy is still the gold standard in the diagnosis of staging of liver fibrosis, but it is a traumatic examination, and there are complications and defects, so its clinical application is limited^[1,2,3,4,5]。 Non-invasive methods for diagnosis of liver fibrosis mainly include elastography and serological indexes. Although serological markers and their diagnostic models can better reflect active liver fibrosis, they are not sensitive to resting liver fibrosis. acoustic radiation force impulse (ARFI) has good application value in the diagnosis of liver fibrosis^[6,7]。 This study aimed to analyze the feasibility of ARFI combined with serological parameters in the diagnosis of hepatic fibrosis staging.

UC is a chronic non-specific inflammatory reaction of colon. Its pathogenesis is not completely clear. The main clinical manifestations are diarrhea, mucous bloody stool, and abdominal pain^[1]。 It was found that the tight junction protein claudin2 can form channels that promote ion secretion^[2]。 Mesalazine, as a new 5-aminosalicylic acid preparation, has an evidence-based basis for becoming a first-line treatment for UC, but it can only simply control the inflammatory response. As a protective agent of intestinal mucosa, montmorillonite powder has strong covering and protecting ability for digestive tract mucosa, repairing and improving the defense function of mucosal barrier against attacking factors, and has the function of balancing normal bacterial flora. In this study, mesalazine, montmorillonite powder and mesalazine combined with montmorillonite powder were used to treat colitis model rats, and the expression of intestinal tight junction protein claudin2 in each group of rats was observed at 12 days of treatment, so as to explore the related mechanism of intestinal mucosal barrier damage and repair, and provide experimental basis for rational combination of drugs in the treatment of UC.

Gastric glomus tumor is rare in clinic, difficult to diagnose before operation, and very easy to misdiagnose. In April 2013, the Second People's Hospital of Liaocheng City, Shandong Province, admitted a patient with gastric glomus tumor confirmed by postoperative pathology. In order to understand the current status of diagnosis and treatment of this disease in China, the domestic literature from 1980 to 2014 was reviewed, and a comprehensive analysis was conducted in combination with this case.

From September 4 to 6, 2015, The 15th Congress of Gastroenterology China (CGC 2015) and The Chinese Congress of Digestive Diseases (CCDD 2015) were held by The Chinese Medical Association It was successfully held in Tianjin Meijiang Convention and Exhibition Center. CGC 2015 was sponsored by Chinese Medical Association and Gastroenterology Branch of Chinese Medical Association, and CCDD 2015 was co-sponsored by Chinese Medical Association, Gastroenterology Branch of Chinese Medical Association, Digestive Endoscopy Branch of Chinese Medical Association and Hepatology Branch of Chinese Medical Association; Tianjin Medical Association and Gastroenterology Branch of Tianjin Medical Association hosted this conference. 5,805 delegates from all over the country attended the meeting, and 1,750 people were broadcast online. It was the largest academic event with the highest academic level in the national gastroenterology community in 2015. Presidents of eight international and national societies, including World Society of Gastroenterology, Asia-Pacific Society of Gastroenterology, American Society of Gastroenterology and British Society of Gastroenterology, attended the meeting to congratulate and give keynote speeches. At the opening ceremony of CCDD 2015 on September 4th, Professor Yang Yunsheng, chairman of the conference and chairman of Gastroenterology Branch of Chinese Medical Association, presided over it. Academician Fan Daiming, honorary chairman of CCDD 2015, Professor Li Zhaoshen, chairman of Digestive Endoscopy Branch of Chinese Medical Association, and Professor Wei Lai, chairman of Hepatology Branch of Chinese Medical Association, attended the conference to congratulate and deliver speeches. At the opening ceremony of the CGC 2015 conference on September 5th, Professor Yang Yunsheng, the chairman of the conference, announced the national anthem and the opening of the conference. Professor Shen Changhong, deputy director of Tianjin Health and Family Planning Commission, Professor Bai Jingmei, vice chairman of Tianjin Science and Technology Association, and Secretary-General Xiong Zhi of Tianjin Medical Association attended the meeting to congratulate.

H.pyloriIt is a pathogenic bacterium of upper gastrointestinal tract diseases such as peptic ulcer and gastric cancer. eradicationH.pyloriCan cure chronic active gastritis, peptic ulcer, gastric MALT lymphoma and other diseases, and may prevent the occurrence of gastric cancer^[1]。 However, successful eradicationH.pyloriThe crowd may reappearH.pyloriInfection, which leads to recurrence of gastritis, peptic ulcer, and MALT lymphoma^[2]。 Therefore,H.pyloriThe sustained eradication state of the disease plays a decisive role in the prevention and treatment of related diseases.

IBD refers to a group of unspecified chronic gastrointestinal inflammatory response diseases of unknown cause, including CD, UC, and indeterminate colitis (IC). It was found that innate immunity, acquired immunity and epithelial cell function play an important role in the development of IBD; However, the pathogenesis of IBD and the role of environmental factors are not well understood^[1]。 Drug therapy based on glucocorticoids and immunosuppressive agents (such as purines and methotrexate) and therapy with biological agents (especially anti-TNF drugs) are applied in early IBD. Although many advances have been made in the treatment of IBD, some patients are ineffective for therapeutic drugs. Some patients even have progressive tissue destruction and potential life shortening. Surgical treatment is an option for some patients, but can lead to short bowel syndrome or significant perforation^[2,3,4,5]。

In addition to the clinical manifestations and biochemical changes of acute pancreatitis (AP), severe acute pancreatitis (SAP) must also be accompanied by persistent organ failure (respiratory, cardiovascular or renal failure that lasts more than 48 h and cannot recover by itself, and may involve one or more organs), and may present peritoneal irritation, ascites, Grey-Turner sign or Cullen sign. The mortality rate of SAP is higher, ranging from 36% to 50%, and the mortality rate is higher if the SAP is co-infected in later stage^[1]。 The natural course of SAP tends to go through two clinical stages: early and late. The early stage (within 1 week) is characterized by systemic inflammatory response syndrome (SIRS) and organ failure. Late (>1 week) characterized by sepsis, systemic and local complications^[2]。 SIRS, organ failure, advanced sepsis and related complications are the leading causes of death in patients with SAP. Patients with SAP will have aggravated SIRS after experiencing major surgical trauma. Therefore, the treatment principle of SAP has evolved from the early aggressive surgical treatment in the past to the early non-surgical individualized treatment now. However, while emphasizing non-surgical individualized treatment, we cannot neglect surgical treatment and avoid going from one extreme to the other. In recent years, with AP diagnostic and classification criteria^[3]As well as many AP guidelines at home and abroad^[2,4]In 2013, China re-formulated the Guidelines for the Diagnosis and Treatment of Acute Pancreatitis in China (2013, Shanghai)^[1](hereinafter referred to as the 2013 Shanghai Guide), which has played an important role in further standardizing the diagnosis and treatment of AP in China.