1988年 · 第101卷第07期

A large pandemic of dengue fever occurred on the Hainan Island, China in 1980. It involved 13 counties including 122 districts. The morbidity was 2146.23/10000 with 64 deaths. The epidemic continued in same areas in 1981, but only sporadic cases were found in 1982. 87 virus strains were isolated from acute-phase sera of 127 patients and 6 from Acdes aegypti in the epidemic area. All of these virus strains were identified as dengue-3 viruses. Results of epidemiologic investigation and virvs isolation proved that Aedes aegypti served as the vector for the transmission of dengue fever on the Hainan Island.

Thirty adult mongrel dogs weighing from 10 to 15 kg were divided randomly into 3 groups, 10 for each. A vascular bundle was transplanted into a piece of bone taken from the ilium and tibia, which was buried in the muscles as an autograft. On the opposite side, a similar piece of bone served as a control without transplanted vascular bundle, Eight weeks after the procedure, all the animals were subjected to gross observation, pulse measurement with radioisotope 169Yb, and histological and electron microscope examinations. Compared with the controls the transplanted bones showed a fresh red surface and had higher values of pulse (P<0.001). Under light microscope, the transplanted vascular bundle proliferated to establish revascularization and the number of osteocytes, osteoblasts and blood vessels was also greater in the vascular transplanted bone than in the controls (P<0.05). A great number of collagenous fibers and abundant new bone trabeculae were seen in the ex perimental bones. These findings were confirmed by electron microscopic examination. AlI of the control bones were dead.

On the basis of enzyme cytochemical staining, T and B lymphocytes and their subpopulations from lymph node suspensions of mouse were analysed after 0, 1, 5 and 10 Gy γ-irradiation with scanning microspectrophotometer. Results showed that the frequency profiles of T cells of normal mouse displayed a dense distribution, while that of B cells a disperse distribution. There were 5 subsets with different slopes in the frequency profiles of T and B cells. The characteristic parameters of the 4th subset of T cells approximated to those of T-helper cells (TH) identified cytochemically by dipeptidylamino-peptidase IV; and after 1, 5 and 10 Gy γ-irradiation, the 4th subset of T cells corresponded with TH cells in radioresistance. It is suggested that both belonged to the same subpopulation of T lymphocytes in nature. The subsets of T and B lymphocytes had different radiosensitivity; B lymphocytes were more radiosensitive than T lymphocytes.

Twenty patients with jugular phlebectasia had the chief symptom of remittent bulging of the neck (unilateral 19, and bilateral 1). Phlebography was performed in 18 patients and showed the lesion was mainly of two types: cystic and cylindrical. Those of external and anterior jugular veins were excised and those of the internal jugular veins were treated by plication. Pathologic studies on 11 excised veins revealed thin venous wall and that smooth muscle fibers were replaced by fibrous tissues. Etiologically, congenital hypoplasia of the venous wall led to the impedance of venous flow secondary to the particular anatomical position at the entry of the thoracic cage. Jugular phlebography demonstrated clearly the size, shape and position of these changes. We found that plication is effective in the treatment of internal jugular phlebectasia and is worth recommending.

The present study includes 4 groups of children: 30 with a history of intrapartum asphyxia, 30 with a history of mild neonatal asphyxia, 15 with a history of severe but transitory neonatal asphyxia, and 30 who had normal deliveries (control group). Psychological and neuropsychological assessments were done when the children were 6 years old. There was no significant diffeenrce among the 4 groups in in telligence quotient, social maturity age, most neuropsychological functions and incidence of attention deficit disorder with hyperactivity. Four test scores in Halstead-Reitan Battery associated with visual-motor functioning showed backwardness in asphyxiated groups. Behavior problems were more frequently seen in the asphyxiated groups than in the control Group.

Gastric emptying (GE) of isotopically labelled solid meals was studied in 17 patients after resection of esophageal carcinoma and in 7 normal subjects as controls. The radioisotope method was used as a quantitative and noninvasive technique for measuring GE. GE in the patients who had tumor resected recently (average 24 days) was delayed, compared with that in normal subjects (P<0.001). The delay of GE was due to truncal vagotomy during cancer resection. GE returned to normal more than 8 months after the operation, and there was no difference be tween the two groups (P>0.05). The mechanism of GE normalization is discussed.

We studied 1400 cases of CNS cysticercosis. 1064 were males and 336 females, with 62.6% aged 31-45 years. According to the classification standard of our country, we divided the cases into epileptic type, 561 cases; subarachnoid type, 126 cases; cerebral parenchymal type, 184 cases; intraventricular type, 102 cases; mixed type, 419 cases; and asymptomatic type, 5 cases. Epilepsy was the most common symptom. Meningitis or adhesive arachnoiditis was the most catastrophic complication of neuro-cysticercosis. Other less common manifestations were stroke, encephalitis, headache without hydrocephalus, cerebral parenchymal inflammation and isolated large cyst, which may mimic intracranial tumors and present a great diagnostic challenge. Virtually, CT scan is the most useful test in diagnosing neuro-cysticercosis. Clinical improvement was attained in 64.4% of the cases, suggesting that praziquantel is effective in the treatment of neurocysticercosis.

Serum calcitonin (CT) concentrations were studied in 235 age- and sex-matched normal Chinese (13-88 years old; 115 males, 120 females) by Eiken RIA kit (Eiken Chemical Co, Ltd, Japan). The subjects were divided into 7 age groups. The range of content tested was 31.8 to 220.6 ng/L. There was no significant sex-related difference in CT mean values in any of the 7 age groups (p>0.05). Statistical analysis showed that CT concentration was influenced significantly by age. Mean CT values were much higher before 30 years old and after 70. There was a significant increase in serum CT in those over 70, which has seldom been reported. The authors believe that the increased CT values in those over 70 are caused by calcium stress, just as in pregnant women and growing children.